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|9 978-1-62703-146-2
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|a Mass Spectrometry of Glycoproteins
|h [electronic resource] :
|b Methods and Protocols /
|c edited by Jennifer J. Kohler, Steven M. Patrie.
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| 250 |
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|a 1st ed. 2013.
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|a Totowa, NJ :
|b Humana Press :
|b Imprint: Humana,
|c 2013.
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| 300 |
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|a XI, 339 p. 90 illus., 12 illus. in color.
|b online resource.
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|a Methods in Molecular Biology,
|x 1940-6029 ;
|v 951
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| 520 |
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|a Glycosylation is the most abundant post-translational modification of proteins. Estimates vary widely, but a common assessment is that upwards of 50% of eukaryotic proteins are modified by some type of glycan. In Mass Spectrometry of Glycoproteins: Methods and Protocols, expert researchers in the field detail many of the methods that are now commonly used for glycoproteomics. These methods and techniques include robust sample preparation techniques; advanced chromatographic strategies for improving dynamic range; state-of-the-art mass spectrometry instrumentation and associated ionization and fragmentation methods; and informatics tools used for identifying glycoproteins and characterizing the associated glycans. Written in the highly successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Mass Spectrometry of Glycoproteins: Methods and Protocol is an essential resource for those who work at the interface of glycobiology and mass spectrometry.
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|a Proteins .
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| 650 |
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|a Mass spectroscopy.
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| 650 |
1 |
4 |
|a Protein Biochemistry.
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| 650 |
2 |
4 |
|a Mass Spectrometry.
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| 700 |
1 |
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|a Kohler, Jennifer J.
|e editor.
|4 edt
|4 http://id.loc.gov/vocabulary/relators/edt
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| 700 |
1 |
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|a Patrie, Steven M.
|e editor.
|4 edt
|4 http://id.loc.gov/vocabulary/relators/edt
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| 710 |
2 |
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|a SpringerLink (Online service)
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| 773 |
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|t Springer Nature eBook
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| 776 |
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8 |
|i Printed edition:
|z 9781627031455
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| 776 |
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8 |
|i Printed edition:
|z 9781627031479
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| 776 |
0 |
8 |
|i Printed edition:
|z 9781493962037
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| 830 |
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|a Methods in Molecular Biology,
|x 1940-6029 ;
|v 951
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| 856 |
4 |
0 |
|u https://doi.org/10.1007/978-1-62703-146-2
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| 912 |
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|a ZDB-2-PRO
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| 950 |
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|a Springer Protocols (Springer-12345)
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