Animal Models of Dementia

Bibliographic Details
Corporate Author: SpringerLink (Online service)
Other Authors: De Deyn, Peter Paul (Editor), Van Dam, Debby (Editor)
Summary:XVI, 732 p.
text
Language:English
Published: Totowa, NJ : Humana Press : Imprint: Humana, 2011.
Edition:1st ed. 2011.
Series:Neuromethods, 48
Subjects:
Online Access:https://doi.org/10.1007/978-1-60761-898-0
Format: Electronic eBook
Table of Contents:
  • General Introduction to Animal Models of Human Conditions
  • Animal Models of Dementia: Ethical Considerations
  • The Role of Rodent Models in the Drug Discovery Pipeline for Dementia
  • Species, Strain, and Gender Issues in the Development and Validation of Animal Models of Dementia
  • Transgenic and Gene Targeted Models of Dementia
  • Transgenic Animals and Intellectual Property Concerns
  • Pathological Validation of Animal Models of Dementia
  • Behavioral Validation in Animal Models of Dementia
  • Pharmacological Validation in Animal Models of Dementia
  • Validation of Animal Models of Dementia: Neurochemical Aspects
  • Validation of Dementia Models Employing Neuroimaging Techniques
  • Drosophila melanogaster as a Model Organism for Dementia
  • Caenorhabditis elegans as a Model Organism for Dementia
  • Zebrafish (Danio rerio) as a Model Organism for Dementia
  • Spontaneous Vertebrate Models of Alzheimer Dementia: Selectively Bred Strains (SAM Strains)
  • Lesion-Induced Vertebrate Models of Alzheimer Dementia
  • Aβ Infusion and Related Models of Alzheimer Dementia
  • APP-Based Transgenic Models: The PDAPP Model
  • APP-Based Transgenic Models: The Tg2576 Model
  • APP-Based Transgenic Models: The APP23 Model
  • Presenilin-Based Transgenic Models of Alzheimer’s Dementia
  • APOE-Based Models of “Pre-Dementia”
  • TAU Models
  • The 3xTg-AD Mouse Model: Reproducing and Modulating Plaque and Tangle Pathology
  • Cognitive Dysfunction in Genetic Mouse Models of Parkinsonism
  • Mouse Models of Metachromatic Leukodystrophy and Adrenoleukodystrophy
  • Animal Models of Amyotrophic Lateral Sclerosis
  • Animal Models of Frontotemporal Dementia
  • CADASIL: Molecular Mechanisms and Animal Models
  • Spontaneously Hypertensive Rat (SHR): An Animal Model of Vascular Brain Disorder
  • Animals Models of Normal Pressure Hydrocephalus
  • Animal Models of Traumatically-Induced Dementia
  • Animal Models of Alcohol-Induced Dementia
  • Animal Models of Metallic Dementia.