Proteomics for Biomarker Discovery Methods and Protocols /

Detalhes bibliográficos
Autor Corporativo: SpringerLink (Online service)
Outros Autores: Brun, Virginie (Editor), Couté, Yohann (Editor)
Resumo:XII, 292 p. 52 illus., 47 illus. in color.
text
Idioma:inglês
Publicado em: New York, NY : Springer New York : Imprint: Humana, 2019.
Edição:1st ed. 2019.
Colecção:Methods in Molecular Biology, 1959
Assuntos:
Acesso em linha:https://doi.org/10.1007/978-1-4939-9164-8
Formato: Recurso Electrónico Livro
Sumário:
  • Pre- and Post-Analytical Factors in Biomarker Discovery
  • Pre-Fractionation of Non-Circulating Biological Fluids to Improve Discovery of Clinically Relevant Protein Biomarkers
  • Serum Exosome Isolation by Size-Exclusion Chromatography for the Discovery and Validation of Preeclampsia-Associated Biomarkers
  • Protein Biomarker Discovery Using Human Blood Plasma Microparticles
  • A Standardized and Reproducible Proteomics Protocol for Bottom-Up Quantitative Analysis of Protein Samples Using SP3 and Mass Spectrometry
  • Analyzing Cerebrospinal Fluid Proteomes to Characterize Central Nervous System Disorders: A Highly Automated Mass Spectrometry-Based Pipeline for Biomarker Discovery
  • Lys-C/Trypsin Tandem-Digestion Protocol for Gel-Free Proteomic Analysis of Colon Biopsies
  • Tube-Gel: A Fast and Effective Sample Preparation Method for High-Throughput Quantitative Proteomics
  • Protein Biomarker Discovery in Non-Depleted Serum by Spectral Library-Based Data-Independent Acquisition Mass Spectrometry
  • Discovering Protein Biomarkers from Clinical Peripheral Blood Mononuclear Cells Using Data-Independent Acquisition Mass Spectrometry
  • Intact Protein Analysis by LC-MS for Characterizing Biomarkers in Cerebrospinal Fluid
  • Detection of Proteoforms Using Top-Down Mass Spectrometry and Diagnostic Ions
  • Development of a Highly Multiplexed SRM Assay for Biomarker Discovery in Formalin-Fixed Paraffin-Embedded Tissues
  • Development and Validation of Multiple Reaction Monitoring (MRM) Assays for Clinical Applications
  • Protein-Level Statistical Analysis of Quantitative Label-Free Proteomics Data with ProStaR
  • Computation and Selection of Optimal Biomarker Combinations by Integrative ROC Analysis using CombiROC
  • PanelomiX for the Combination of Biomarkers
  • Designing an In Silico Strategy to Select Tissue-Leakage Biomarkers Using the Galaxy Framework.