Progranulin Methods and Protocols /
| 団体著者: | |
|---|---|
| その他の著者: | , , |
| 要約: | XIII, 363 p. 79 illus., 56 illus. in color. text |
| 言語: | 英語 |
| 出版事項: |
New York, NY :
Springer New York : Imprint: Humana,
2018.
|
| 版: | 1st ed. 2018. |
| シリーズ: | Methods in Molecular Biology,
1806 |
| 主題: | |
| オンライン･アクセス: | https://doi.org/10.1007/978-1-4939-8559-3 |
| フォーマット: | 電子媒体 図書 |
目次:
- A Brief Overview of Progranulin in Health and Disease
- Chromatographic Methods for the Purification of Granulin Peptides
- Methods for Expression and Purification of Biologically Active Recombinant Progranulin
- Large-Scale Generation of Recombinant Granulin Peptides in E. coli
- Nuclear Magnetic Resonance Spectroscopy in Analysis of Granulin Three-Dimensional Structure and Cysteine Bridging
- Data Mining: Applying the AD&FTD Mutation Database to Progranulin
- Measurement of Circulating Progranulin (PGRN/GP88/GEP) by Enzyme-Linked Immunosorbent Assay and Application in Human Diseases
- Immunohistochemical Detection of Progranulin (PGRN/GP88/GEP) in Tumor Tissues as a Cancer Prognostic Biomarker
- Analysis of Progranulin-Mediated Akt and MAPK Activation
- Mouse Monoclonal Antibodies Against Progranulin (PGRN/GEP) as Therapeutics in Preclinical Cancer Models
- Methods to Analyze the Role of Progranulin (PGRN/GEP) on Cancer Stem Cell Features
- Methods to Study the Role of Progranulin in the Tumor Microenvironment
- Methods to Investigate the Molecular Basis of Progranulin Action on Neurons In Vivo using Caenorhabditis elegans
- The Use of Caenorhabditis elegans to Study Progranulin in the Regulation of Programmed Cell Death and Stress Response
- Application of Zebrafish and Knockdown Technology to Define Progranulin Neuronal Function
- Methods to Investigate the Molecular Basis of Progranulin Actions on Brain and Behavior In Vivo Using Knockout Mice
- Methods to Investigate the Protection Againts Neurodegenerative Disorders Provided by Progranulin Gene Transfer in the Brain
- The Interaction between Progranulin with Sortilin and the Lysosome
- Methods to Study the Role of Progranulin in Preimplanatation Mouse Embryo Development
- Establishment of a Modified Collagen-Induced Arthritis Mouse Model to Investigate the Anti-Inflammatory Activity of Progranulinin Inflammatory Arthritis
- Methods for Studying the Function of Progranulin in Atherosclerosis using Both Knockout Mice Models and In Vitro Studies
- Methods to Investigate the Roles of Prgranulin in Angiogenesis Using In Vitro Strategies and Transgenic Mouse Models.