Electrochemical histamine detection: Advances in sensor design, mechanisms, and applications; Microchemical Journal; Vol. 225
| Parent link: | Microchemical Journal.— .— Amsterdam: Elsevier Science Publishing Company Inc. Vol. 225.— 2026.— Article number 118157, 27 p. |
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| Other Authors: | , , , , |
| Summary: | Title screen The chemical histamine is an important molecule that acts as a transmitter in the nervous system and a mediator in the immune system and can pose serious health problems. While conventional methods of histamine determination use chromatography and immunoassays, these methods are generally limited by requiring expensive equipment, complex protocols, and trained professionals to perform them. Thus, there is growing interest in electrochemical sensing technology as a cost-effective, portable and sensitive method of determining histamine levels. This paper presents a critical evaluation of electrochemical histamine sensors developed over the last decade based on three distinct design paradigms: First, non-biological platforms consisting of nano-enhanced electrode surfaces that support the electrocatalytic oxidation of histamine; second, biosensors containing enzymes such as histamine dehydrogenase or diamine oxidase that recognize histamine selectively; and third, biomimetic systems incorporating molecularly imprinted polymers or aptamers that combine synthetic durability with molecular specificity. This review critically evaluates the performance of these electrochemical histamine sensors using various metrics, including the role of coordination chemistry, in addition to some of the persistent analytical challenges of electrochemical histamine sensors. Furthermore, this review highlights some of the recent trends in this area of research, including hybrid architectures that integrate both abiotic catalysis with biomimetic recognition; the development of dual-analyte detection strategies to enable comprehensive profiling of biogenic amines; and the use of artificial intelligence to improve the selectivity of electrochemical histamine sensors. Finally, this review maps the characteristics of electrochemical histamine sensors to various application contexts, ranging from dockside fish freshness testing to point of care clinical diagnostics. This review provides a useful guide for researchers who seek to translate laboratory-based innovations into regulatory-compliant tools that will ultimately contribute to safer food and better healthcare for individuals around the world Текстовый файл AM_Agreement |
| Language: | English |
| Published: |
2026
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| Subjects: | |
| Online Access: | https://doi.org/10.1016/j.microc.2026.118157 |
| Format: | Electronic Book Chapter |
| KOHA link: | https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=686538 |