Aerobic Oxidation of Imidazolines to 2-Arylimidazoles Using CuSO4∙H2O as a Catalyst; Synthesis; Vol. 57, iss. 23
| Parent link: | Synthesis.— .— New-York: Thieme Vol. 57, iss. 23.— 2025.— P. 3611-3616 |
|---|---|
| Other Authors: | Myachina K. A. Kristina Alekseevna, Semenov A. V. Artem Valerjevich, Shurikov M. K. Matvey Konstantinovich, Dar’in D. V. Dmitry, Baykov S. V. Sergey Valentinovich, Yusubov M. S. Mekhman Suleiman-Ogly (Suleimanovich), Soldatova N. S. Nataliya Sergeevna, Postnikov P. S. Pavel Sergeevich |
| Summary: | Title screen midazoles are considered the merit heterocyclic moiety in medicinal chemistry and drug design. Here, we report on a convenient method for the aerobic oxidation of imidazolines under mild conditions using the cheap and available CuSO4∙5H2O as the catalyst. The proposed method allows one to prepare 2-arylimidazoles bearing electron-donating and -withdrawing groups in good and quantitative yields. The developed procedure is applicable for the preparation of labile and oxidation-intolerant heterocyclic moieties Текстовый файл AM_Agreement |
| Language: | English |
| Published: |
2025
|
| Subjects: | |
| Online Access: | https://doi.org/10.1055/a-2705-5409 |
| Format: | Electronic Book Chapter |
| KOHA link: | https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=683317 |
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