Mild and General Protocol for Selective Deacetylation of Acetyl/Benzoyl-Protected Carbohydrates; Journal of Organic Chemistry; Vol. 89, iss.14
| Parent link: | Journal of Organic Chemistry.— .— Washington: American Chemical Society Vol. 89, iss.14.— 2025.— P. 10021-10026 |
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| अन्य लेखक: | , , , , , , |
| सारांश: | Title screen Herein, we report a mild and general protocol for chemoselective deacetylation of mixed acetyl- and benzoyl-protected carbohydrates under mild acidic conditions. The protocol allows quick access to partially protected carbohydrates, which serve as versatile synthetic intermediates during the total synthesis of various mono- and oligosaccharide targets. The applicability of the developed protocol was successfully demonstrated on a range of carbohydrate substrates of various configurations and substitution patterns featuring functionalized aliphatic and aromatic aglycones. The protocol has shown excellent compatibility with the widely used O-anomeric protecting groups, prespacer aglycones, and thioglycoside glycosyl donors Текстовый файл |
| भाषा: | अंग्रेज़ी |
| प्रकाशित: |
2025
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| विषय: | |
| ऑनलाइन पहुंच: | https://doi.org/10.1021/acs.joc.4c00900 |
| स्वरूप: | इलेक्ट्रोनिक पुस्तक अध्याय |
| KOHA link: | https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=680034 |