Mild and General Protocol for Selective Deacetylation of Acetyl/Benzoyl-Protected Carbohydrates

Bibliographic Details
Parent link:	Journal of Organic Chemistry.— .— Washington: American Chemical Society Vol. 89, iss.14.— 2025.— P. 10021-10026
Other Authors:	Abramov A. A. Aleksandr Aleksandrovich, Zinin A. I. Aleksandr Ivanovich, Kolotyrkina N. G. Natalya, Kononov L. O., Shatskiy A. Andrey, Karkas M. D. Markus, Stepanova E. V. Elena Vladimirovna
Summary:	Title screen Herein, we report a mild and general protocol for chemoselective deacetylation of mixed acetyl- and benzoyl-protected carbohydrates under mild acidic conditions. The protocol allows quick access to partially protected carbohydrates, which serve as versatile synthetic intermediates during the total synthesis of various mono- and oligosaccharide targets. The applicability of the developed protocol was successfully demonstrated on a range of carbohydrate substrates of various configurations and substitution patterns featuring functionalized aliphatic and aromatic aglycones. The protocol has shown excellent compatibility with the widely used O-anomeric protecting groups, prespacer aglycones, and thioglycoside glycosyl donors Текстовый файл
Published:	2025
Subjects:	электронный ресурс труды учёных ТПУ Carbohydrates Chemical reactions Free radicals Organic compounds Protective groups
Online Access:	https://doi.org/10.1021/acs.joc.4c00900
Format:	Electronic Book Chapter
KOHA link:	https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=680034

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