An N-Acetyl-L-Cysteine Impedance Sensor for Assessing Antioxidant Activity against Hydroxyl Radicals; Journal of Analytical Chemistry; Vol. 79, iss. 6

An N-Acetyl-L-Cysteine Impedance Sensor for Assessing Antioxidant Activity against Hydroxyl Radicals; Journal of Analytical Chemistry; Vol. 79, iss. 6

التفاصيل البيبلوغرافية
Parent link:	Journal of Analytical Chemistry.— .— New York: Springer Science+Business Media LLC. Vol. 79, iss. 6.— 2024.— P. 663–670
مؤلف مشترك:	National Research Tomsk Polytechnic University (570)
مؤلفون آخرون:	Erkovich A. V. Alina Vadimovna, Korotkova E. I. Elena Ivanovna, Dorozhko E. V. Elena Vladimirovna, Solomonenko A. N. Anna Nikolaevna, Aseeva N. V. Natalya Valerevna
الملخص:	Title screen The hydroxyl radical is the most aggressive and dangerous product of incomplete oxygen reduction in a body, making its determination and the effect of various antioxidants on the inhibition of OH radicals a pertinent task. We propose an impedance sensor for the determination of hydroxyl radicals, based on a graphite electrode modified with electrochemically deposited gold and a self-assembled monolayer of N-acetyl-L-cysteine (NAC). The use of NAC ensures the high selectivity of the sensor, and employing non-Faradaic impedance as a method of recording the analytical signal ensures the limit of detection for OH radicals at the level 0.01 nM with a linearity range of detectable concentrations from 0.08 to 8 nM. The developed sensor has been successfully used to assess the activity of certain antioxidants (ascorbic acid, glutathione, coenzyme Q10) towards OH radicals Текстовый файл AM_Agreement
اللغة:	الإنجليزية
منشور في:	2024
الموضوعات:	электронный ресурс труды учёных ТПУ hydroxyl radical impedance spectroscopy antioxidant activity ascorbic acid glutathione coenzyme Q10
الوصول للمادة أونلاين:	https://doi.org/10.1134/S1061934824700035
التنسيق:	MixedMaterials الكتروني فصل الكتاب
KOHA link:	https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=675854

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