Alkylverdazyls as a Source of Alkyl Radicals for Light-Triggered Cancer Cell Death

Dades bibliogràfiques
Parent link:Molecular Pharmaceutics
Vol. 19, iss. 1.— 2022.— [P. 354-357]
Autor corporatiu: Национальный исследовательский Томский политехнический университет Исследовательская школа химических и биомедицинских технологий
Altres autors: Votkina D. E. Darjya Evgenjevna, Plotnikov E. V. Evgeny Vladimirovich, Petunin P. V. Pavel Vasilievich, Berdinskaya E. S. Elizaveta Sergeevna, Tretyakova M. S. Maria Sergeevna, Audran G. Gerard, Marque S. R. A. Sylvain, Postnikov P. S. Pavel Sergeevich
Sumari:Title screen
Two alkylated verdazyl radicals (AlkVZs) were investigated as active compounds for photoinitiated controlled MCF-7 cell death. Observed results unambiguously showed that AlkVZ could be a potential structural moiety for the design of a novel family of photodynamic therapy agents. The main advantage of the proposed substances is an oxygen-independent generation of active radicals, which play a pivotal role in the treatment of oxygen-deficient tumors.
Режим доступа: по договору с организацией-держателем ресурса
Publicat: 2022
Matèries:
Accés en línia:https://doi.org/10.1021/acs.molpharmaceut.1c00780
Format: Electrònic Capítol de llibre
KOHA link:https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=668692

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