Alkylverdazyls as a Source of Alkyl Radicals for Light-Triggered Cancer Cell Death

Alkylverdazyls as a Source of Alkyl Radicals for Light-Triggered Cancer Cell Death

Bibliographic Details
Parent link:Molecular Pharmaceutics
Vol. 19, iss. 1.— 2022.— [P. 354-357]
Corporate Author: Национальный исследовательский Томский политехнический университет Исследовательская школа химических и биомедицинских технологий
Other Authors: Votkina D. E. Darjya Evgenjevna, Plotnikov E. V. Evgeny Vladimirovich, Petunin P. V. Pavel Vasilievich, Berdinskaya E. S. Elizaveta Sergeevna, Tretyakova M. S. Maria Sergeevna, Audran G. Gerard, Marque S. R. A. Sylvain, Postnikov P. S. Pavel Sergeevich
Summary:Title screen
Two alkylated verdazyl radicals (AlkVZs) were investigated as active compounds for photoinitiated controlled MCF-7 cell death. Observed results unambiguously showed that AlkVZ could be a potential structural moiety for the design of a novel family of photodynamic therapy agents. The main advantage of the proposed substances is an oxygen-independent generation of active radicals, which play a pivotal role in the treatment of oxygen-deficient tumors.
Режим доступа: по договору с организацией-держателем ресурса
Published: 2022
Subjects:
труды учёных ТПУ
электронный ресурс
alkylated verdazyls
cancer cell death
photolysis
алкилвердазилы
алкилированные вердазильные радикалы
раковые клетки
онкологические заболевания
Online Access:https://doi.org/10.1021/acs.molpharmaceut.1c00780
Format: Electronic Book Chapter
KOHA link:https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=668692

Internet

https://doi.org/10.1021/acs.molpharmaceut.1c00780

Similar Items