Alkylverdazyls as a Source of Alkyl Radicals for Light-Triggered Cancer Cell Death
| Parent link: | Molecular Pharmaceutics Vol. 19, iss. 1.— 2022.— [P. 354-357] |
|---|---|
| Співавтор: | |
| Інші автори: | , , , , , , , |
| Резюме: | Title screen Two alkylated verdazyl radicals (AlkVZs) were investigated as active compounds for photoinitiated controlled MCF-7 cell death. Observed results unambiguously showed that AlkVZ could be a potential structural moiety for the design of a novel family of photodynamic therapy agents. The main advantage of the proposed substances is an oxygen-independent generation of active radicals, which play a pivotal role in the treatment of oxygen-deficient tumors. Режим доступа: по договору с организацией-держателем ресурса |
| Мова: | Англійська |
| Опубліковано: |
2022
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| Предмети: | |
| Онлайн доступ: | https://doi.org/10.1021/acs.molpharmaceut.1c00780 |
| Формат: | Електронний ресурс Частина з книги |
| KOHA link: | https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=668692 |
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| 200 | 1 | |a Alkylverdazyls as a Source of Alkyl Radicals for Light-Triggered Cancer Cell Death |f D. E. Votkina, E. V. Plotnikov, P. V. Petunin [et al.] | |
| 203 | |a Text |c electronic | ||
| 300 | |a Title screen | ||
| 330 | |a Two alkylated verdazyl radicals (AlkVZs) were investigated as active compounds for photoinitiated controlled MCF-7 cell death. Observed results unambiguously showed that AlkVZ could be a potential structural moiety for the design of a novel family of photodynamic therapy agents. The main advantage of the proposed substances is an oxygen-independent generation of active radicals, which play a pivotal role in the treatment of oxygen-deficient tumors. | ||
| 333 | |a Режим доступа: по договору с организацией-держателем ресурса | ||
| 461 | |t Molecular Pharmaceutics | ||
| 463 | |t Vol. 19, iss. 1 |v [P. 354-357] |d 2022 | ||
| 610 | 1 | |a труды учёных ТПУ | |
| 610 | 1 | |a электронный ресурс | |
| 610 | 1 | |a alkylated verdazyls | |
| 610 | 1 | |a cancer cell death | |
| 610 | 1 | |a photolysis | |
| 610 | 1 | |a алкилвердазилы | |
| 610 | 1 | |a алкилированные вердазильные радикалы | |
| 610 | 1 | |a раковые клетки | |
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| 701 | 1 | |a Plotnikov |b E. V. |c chemist |c Associate Professor of Tomsk Polytechnic University, Candidate of Chemical Sciences |f 1983- |g Evgeny Vladimirovich |3 (RuTPU)RU\TPU\pers\32469 | |
| 701 | 1 | |a Petunin |b P. V. |c chemist |c Associate Professor of Tomsk Polytechnic University, Candidate of Chemical Sciences |f 1982- |g Pavel Vasilievich |3 (RuTPU)RU\TPU\pers\36904 |9 19933 | |
| 701 | 1 | |a Berdinskaya |b E. S. |g Elizaveta Sergeevna | |
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