Synthesis of Radioiodinated Compounds. Classical Approaches and Achievements of Recent Years

Bibliographic Details
Parent link:International Journal of Molecular Sciences
Vol. 23, iss. 22.— 2022.— [13789, 41 p. ]
Corporate Author: Национальный исследовательский Томский политехнический университет Исследовательская школа химических и биомедицинских технологий
Other Authors: Petrov S. A. Stanislav Aleksandrovich, Yusubov M. S. Mekhman Suleiman-Ogly (Suleimanovich), Beloglazkina E. K. Elena Kimovna, Nenaydenko V. G. Valentin Georgievich
Summary:This review demonstrates the progress in the synthesis of radioiodinated compounds over the past decade. The possibilities and limitations of radiopharmaceuticals with different iodine isotopes, as well as the synthesis of low and high molecular weight compounds containing radioiodine, are discussed. An analysis of synthesis strategies, substrate frameworks, isolation methods, and metabolic stability, and the possibility of industrial production of radioiodinated organic derivatives which can find applications in the synthesis of drugs and diagnostics are presented.
Published: 2022
Subjects:
Online Access:https://doi.org/10.3390/ijms232213789
Format: Electronic Book Chapter
KOHA link:https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=668610