Transition-Metal-Free Base-Controlled C−N Coupling Reactions: Selective Mono Versus Diarylation of Primary Amines with 2-Chlorobenzimidazoles; Advanced Synthesis and Catalysis; Vol. 363, iss. 5

Transition-Metal-Free Base-Controlled C−N Coupling Reactions: Selective Mono Versus Diarylation of Primary Amines with 2-Chlorobenzimidazoles; Advanced Synthesis and Catalysis; Vol. 363, iss. 5

Detalles Bibliográficos
Parent link:Advanced Synthesis and Catalysis
Vol. 363, iss. 5.— 2021.— [P. 1408-1416]
Autor Corporativo: Национальный исследовательский Томский политехнический университет Исследовательская школа химических и биомедицинских технологий
Outros autores: Wei Sang, Yan-Yan Gong, Hua Cheng, Rui Zhang, Ye Yuan, Guang-Gao Fan, Zhi-Qin Wang, Cheng Chen, Verpoort F. V. K. Frensis Valter Kornelius
Summary:Title screen
Herein, a base-controlled protocol was developed for the C−N coupling of primary amines and 2-chlorobenzimidazoles, affording a handful of secondary or tertiary amines in a selective fashion. Moreover, this protocol was realized under transition-metal-free conditions, and the variation of the base from iPr2NH to LiOtBu completely switched the selectivity from monoarylation to diarylation. Further investigations elucidated that the variety, intrinsic basicity and amount of the utilized bases considerably affected these reactions.
Idioma:inglés
Publicado: 2021
Subjects:
электронный ресурс
труды учёных ТПУ
transition-metal-free
base-controlled
CN coupling
diarylation
monoarylation
2-aminobenzimida-zoles
переходные металлы
амины
Acceso en liña:https://doi.org/10.1002/adsc.202001365
Formato: MixedMaterials Electrónico Capítulo de libro
KOHA link:https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=667545

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