11H-Indeno[1,2-b]quinoxalin-11-one 2-(4-Ethylbenzylidene)hydrazone; Molbank; Vol. 2021, iss. 4

11H-Indeno[1,2-b]quinoxalin-11-one 2-(4-Ethylbenzylidene)hydrazone; Molbank; Vol. 2021, iss. 4

Xehetasun bibliografikoak
Parent link:Molbank
Vol. 2021, iss. 4.— 2021.— [M1299, 7 p.]
Egile nagusia: Kovrizhina A. R. Anastasia Ruslanovna
Erakunde egilea: Национальный исследовательский Томский политехнический университет Инженерная школа новых производственных технологий Научно-образовательный центр Н. М. Кижнера
Beste egile batzuk: Samorodova E. I. Elizaveta Innokentjevna, Khlebnikov A. I. Andrey Ivanovich
Gaia:Title screen
11H-Indeno[1,2-b]quinoxaline derivatives present an important type of nitrogen-containing heterocyclic compound that are useful intermediate products in organic synthesis and have potential pharmaceutical applications. A new 11H-indeno[1,2-b]quinoxalin-11-one-2-(4-ethylbenzylidene)hydrazone (compound 3) was synthesized. Compound 3 is the first example of an azine derivative based on the 11H-indeno[1,2-b]quinoxaline system. The Z,E-isomerism of compound 3 was investigated by DFT calculations. Bioavailability was evaluated in silico using ADME predictions. According to the ADME results, compound 3 is potentially highly bioavailable and has potential to be used for the treatment of neuroinflammation and ischemia–reperfusion injury.
Hizkuntza:ingelesa
Argitaratua: 2021
Gaiak:
электронный ресурс
труды учёных ТПУ
azine
aldazine
11H-indeno[1,2-b]quinoxalin-11-one
DFT
азины
органический синтез
биодоступность
ишемия
азотсодержащие соединения
Sarrera elektronikoa:https://doi.org/10.3390/M1299
Formatua: MixedMaterials Baliabide elektronikoa Liburu kapitulua
KOHA link:https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=666275

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