2-(2-(Fluorosulfonyloxy)phenyl)benzoxazole; Molbank; Vol. 2021, iss. 3
| Parent link: | Molbank Vol. 2021, iss. 3.— 2021.— [M1242, 5 p.] |
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| প্রধান লেখক: | |
| সংস্থা লেখক: | , |
| অন্যান্য লেখক: | , |
| সংক্ষিপ্ত: | Title screen The fluorosulfate derivatives of benzoxazole attract attention since benzoxazole-based compounds have a wide range of biological activities, and the ability of the -SO2F group to react with various functional groups makes it possible to synthesize various new derivatives. The new 2-(2-(fluorosulfonyloxy)phenyl)benzoxazole (2) has been synthesized by the SuFEx click reaction in a two-chamber reactor. Compound 2 is the first example of a benzoxazole derivative with a fluorosulfate-containing substituent at position two of the benzoxazole heterocycle. The anti-cancer potency of 2 was evaluated in silico using molecular docking. The docking results suggest that title compound 2 is of great interest for further studies as a possible anaplastic lymphoma kinase inhibitor. |
| ভাষা: | ইংরেজি |
| প্রকাশিত: |
2021
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| বিষয়গুলি: | |
| অনলাইন ব্যবহার করুন: | https://doi.org/10.3390/M1242 |
| বিন্যাস: | বৈদ্যুতিক গ্রন্থের অধ্যায় |
| KOHA link: | https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=665346 |