A copper nanoparticle-based electrochemical immunosensor for carbaryl detection

Manylion Llyfryddiaeth
Parent link:Talanta
Vol. 228.— 2021.— [122174, 8p.]
Awdur Corfforaethol: Национальный исследовательский Томский политехнический университет Инженерная школа природных ресурсов Отделение химической инженерии
Awduron Eraill: Dorozhko E. V. Elena Vladimirovna, Gashevskaya A. S. Anna Sergeevna, Korotkova E. I. Elena Ivanovna, Barek J. Jiri, Vyskocil V. Vlastimil, Eremin S. A. Sergey Aleksandrovich, Galunin E. V. Evgeny Valerjevich, Saqib M. Muhammad
Crynodeb:Title screen
A hapten-protein conjugate with copper nanoparticles (Hap-Car-BSA@CuNPs) was first synthesized in the present work for the determination of carbaryl. The copper nanoparticles (CuNPs) of the conjugate were used as elec-trochemical labels in the direct solid-phase competitive determination of carbaryl residues in flour from different crops. The signal was read by linear sweep anodic stripping voltammetry (LSASV) of copper (through the electrochemical stripping of accumulated elemental copper) on a gold-graphite electrode (GGE). To form a recognition receptor layer of monoclonal antibodies against the carbaryl on the surface of the GGE, 1-ethyl-3-(3- dimethylaminopropyl)carbodiimide hydrochloride (EDC) and 1-hydroxy-2,5-pyrrolidinedione (NHS) were used as the best covalent cross-linkers. The concentrations of the antibodies and the Hap-Car-BSA@CuNPs conjugate were optimized for carbaryl detection by the electrochemical immunosensor. The electrochemical immunosensor can be used for highly sensitive determination of carbaryl residues in flour samples in the concentration range 0.8-32.3 [mu]•kg. The present work paves the path for a novel method for monitoring carbaryl in other food products, drinks, and soil samples.
Режим доступа: по договору с организацией-держателем ресурса
Cyhoeddwyd: 2021
Pynciau:
Mynediad Ar-lein:https://doi.org/10.1016/j.talanta.2021.122174
Fformat: Electronig Pennod Llyfr
KOHA link:https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=665178