Cell response to PLA scaffolds functionalized with various seaweed polysaccharides

Cell response to PLA scaffolds functionalized with various seaweed polysaccharides

Dades bibliogràfiques
Parent link:International Journal of Polymeric Materials and Polymeric Biomaterials
Vol. 71, iss. 2.— 2020.— [9 p.]
Autor corporatiu: Национальный исследовательский Томский политехнический университет Исследовательская школа химических и биомедицинских технологий
Altres autors: Ozaltin K. Kadir, Vargun E. Elif, Di Martino A. Antonio, Capakova Zd. Zdenka, Lehocky M. Marian, Humpolicek P. Petr, Kazantseva N. E. Nataljya, Saha P. Petr
Sumari:Title screen
The porous polylactic acid matrix has been particularly developed as a scaffold in tissue engineering, drug loading, and wound dressing. However, the loading of active chemical compounds is challenging due to its highly hydrophobic nature and lack of functional groups for chemical bonding. Plasma treatment is a fast, heat and chemical-free solution to increase its hydrophilicity by oxidative functional groups and physical etching. In this study, a highly porous PLA scaffold was obtained by polyethylene glycol pore formation agent and treated by radiofrequency (RF) air plasma. Fucoidan from Fucus vesiculosus, Macrocystis pyrifera, and Undaria pinnatifida were used to immobilize onto the activated porous PLA surface for use as medicated wound dressings. The chemical composition and morphology were investigated by FTIR, SEM-EDS analysis, and cytocompatibility assay was studied mouse embryonic fibroblast cells (NIH/3T3).
Idioma:anglès
Publicat: 2020
Matèries:
электронный ресурс
труды учёных ТПУ
polylactic acid
fucoidan
PLA scaffold
fibroblast cell
plasma treatment
полимолочная кислота
строительные леса
плазменная обработка
Accés en línia:https://doi.org/10.1080/00914037.2020.1798443
Format: Electrònic Capítol de llibre
KOHA link:https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=664916

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