The deposition of thin titanium-nitrogen coatings on the surface of PCL-basedscaffolds for vascular tissue engineering; Applied Physics Letters; Vol. 112, iss. 15

Bibliografiske detaljer
Parent link:Applied Physics Letters
Vol. 112, iss. 15.— 2018.— [153705, 5 p.]
Corporate Authors: Национальный исследовательский Томский политехнический университет Инженерная школа ядерных технологий Научно-образовательный центр Б. П. Вейнберга, Национальный исследовательский Томский политехнический университет Инженерная школа ядерных технологий Отделение ядерно-топливного цикла, Национальный исследовательский Томский политехнический университет Инженерная школа ядерных технологий Лаборатория плазменных гибридных систем
Andre forfattere: Kudryavtseva V. L. Valeriya Lvovna, Stankevich K. S. Ksenia Sergeevna, Kibler E. V. Elina Vitaljevna, Golovkin A. S. Aleksey Sergeevich, Mishanin A. I. Aleksandr Igorevich, Bolbasov E. N. Evgeny Nikolaevich, Choynzonov E. L. Evgeny Lkhamatsyrenovich, Tverdokhlebov S. I. Sergei Ivanovich
Summary:Title screen
Biodegradable polymer scaffolds for tissue engineering is a promising technology for therapies of patients suffering from the loss of tissue or its function including cardiac tissues. However, limitations such as hydrophobicity of polymers prevent cell attachment, cell conductivity, and endothelialization. Plasma modification of polymers allows producing materials for an impressive range of applications due to their unique properties. Here, we demonstrate the possibility of bioresorbable electrospun polycaprolacton (PCL) scaffold surface modification by reactive magnetron sputtering of the titanium target in a nitrogen atmosphere. The influence of the plasma treatment time on the structure and properties of electrospun PCL scaffolds was studied. We show that the plasma treatment does not change the physico-mechanical properties of electrospun PCL scaffolds, leads to an increase in PCL scaffold biocompatibility, and, simultaneously, increases their hydrophilicity. In conclusion, this modification method opens a route to producing scaffolds with enhanced biocompatibility for tissue engineered vascular grafts.
Режим доступа: по договору с организацией-держателем ресурса
Sprog:engelsk
Udgivet: 2018
Fag:
Online adgang:https://doi.org/10.1063/1.5017580
Format: MixedMaterials Electronisk Book Chapter
KOHA link:https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=664504

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200 1 |a The deposition of thin titanium-nitrogen coatings on the surface of PCL-basedscaffolds for vascular tissue engineering  |f V. L. Kudryavtseva, K. S. Stankevich, E. V. Kibler [et al.] 
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300 |a Title screen 
320 |a [References: 34 tit.] 
330 |a Biodegradable polymer scaffolds for tissue engineering is a promising technology for therapies of patients suffering from the loss of tissue or its function including cardiac tissues. However, limitations such as hydrophobicity of polymers prevent cell attachment, cell conductivity, and endothelialization. Plasma modification of polymers allows producing materials for an impressive range of applications due to their unique properties. Here, we demonstrate the possibility of bioresorbable electrospun polycaprolacton (PCL) scaffold surface modification by reactive magnetron sputtering of the titanium target in a nitrogen atmosphere. The influence of the plasma treatment time on the structure and properties of electrospun PCL scaffolds was studied. We show that the plasma treatment does not change the physico-mechanical properties of electrospun PCL scaffolds, leads to an increase in PCL scaffold biocompatibility, and, simultaneously, increases their hydrophilicity. In conclusion, this modification method opens a route to producing scaffolds with enhanced biocompatibility for tissue engineered vascular grafts. 
333 |a Режим доступа: по договору с организацией-держателем ресурса 
461 |t Applied Physics Letters 
463 |t Vol. 112, iss. 15  |v [153705, 5 p.]  |d 2018 
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701 1 |a Kudryavtseva  |b V. L.  |c physicist  |c Engineer of Tomsk Polytechnic University  |f 1993-  |g Valeriya Lvovna  |3 (RuTPU)RU\TPU\pers\38564  |9 20822 
701 1 |a Stankevich  |b K. S.  |c Physicist  |c Engineer Tomsk Polytechnic University  |f 1992-  |g Ksenia Sergeevna  |3 (RuTPU)RU\TPU\pers\37546  |9 20415 
701 1 |a Kibler  |b E. V.  |c specialist in the field of nuclear technologies  |c Engineer of Tomsk Polytechnic University  |f 1995-  |g Elina Vitaljevna  |3 (RuTPU)RU\TPU\pers\46672  |9 22328 
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701 1 |a Bolbasov  |b E. N.  |c physicist  |c Senior Researcher at Tomsk Polytechnic University, Candidate of Technical Sciences  |f 1981-  |g Evgeny Nikolaevich  |3 (RuTPU)RU\TPU\pers\30857  |9 15103 
701 1 |a Choynzonov  |b E. L.  |c physicist  |c chief expert of Tomsk Polytechnic University  |f 1952-  |g Evgeny Lkhamatsyrenovich  |3 (RuTPU)RU\TPU\pers\34575 
701 1 |a Tverdokhlebov  |b S. I.  |c physicist  |c Associate Professor of Tomsk Polytechnic University, Candidate of physical and mathematical science  |f 1961-  |g Sergei Ivanovich  |3 (RuTPU)RU\TPU\pers\30855  |9 15101 
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