A study of products of tetrakis(hydroxymethyl)glycoluril dehydroxymethylation in aqueous solutions

A study of products of tetrakis(hydroxymethyl)glycoluril dehydroxymethylation in aqueous solutions

Bibliografiska uppgifter
Parent link:Russian Chemical Bulletin
Vol. 70, iss. 1.— 2021.— [P. 140-147]
Institutionell upphovsman: Национальный исследовательский Томский политехнический университет Инженерная школа новых производственных технологий Научно-образовательный центр Н. М. Кижнера
Övriga upphovsmän: Panshina S. Svetlana, Ponomarenko O. V., Bakibaev A. A. Abdigali Abdimanapovich, Sidelnikov V. S. Vladimir Sergeevich, Kurgachev D. A. Dmitry Andreevich, Malkov V. S. Viktor Sergeevich, Khlebnikov A. I. Andrey Ivanovich, Tasheno A. K. Auezkhan Karipkhanovich
Sammanfattning:Title screen
It was found that tetrakis(hydroxymethyl)glycoluril is unstable in aqueous solutions and undergoes stepwise dehydroxymethylation. The products of this process were identified by HPLC, 1D and 2D NMR spectroscopy. The main product of hydrolytic degradation at room temperature is tris(hydroxymethyl)glycoluril, which may be conditioned by the thermodynamic characteristics of the reaction. Further dehydroxymethylation to give di- and monohydroxymethyl glycoluril derivatives occurs under more severe conditions.
Режим доступа: по договору с организацией-держателем ресурса
Språk:engelska
Publicerad: 2021
Ämnen:
электронный ресурс
труды учёных ТПУ
tetrakis(hydroxymethyl)glycoluril
tris(hydroxymethyl)glycoluril
dehydroxymethylation
HPLC
NMR
COSY
HMBC
quantum chemical calculations
Länkar:https://doi.org/10.1007/s11172-021-3068-8
Materialtyp: Elektronisk Bokavsnitt
KOHA link:https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=664106
Beskrivning
Sammanfattning:Title screen
It was found that tetrakis(hydroxymethyl)glycoluril is unstable in aqueous solutions and undergoes stepwise dehydroxymethylation. The products of this process were identified by HPLC, 1D and 2D NMR spectroscopy. The main product of hydrolytic degradation at room temperature is tris(hydroxymethyl)glycoluril, which may be conditioned by the thermodynamic characteristics of the reaction. Further dehydroxymethylation to give di- and monohydroxymethyl glycoluril derivatives occurs under more severe conditions.
Режим доступа: по договору с организацией-держателем ресурса
DOI:10.1007/s11172-021-3068-8

Liknande verk