Enhancement of the adhesive strength of antithrombogenic and hemocompatible a-C:H:SiOx films to polypropylene

Bibliographic Details
Parent link:Surface and Coatings Technology
Vol. 399.— 2020.— [126132, 12 p.]
Corporate Authors: Национальный исследовательский Томский политехнический университет Инженерная школа ядерных технологий Научно-образовательный центр Б. П. Вейнберга, Национальный исследовательский Томский политехнический университет Исследовательская школа физики высокоэнергетических процессов
Other Authors: Grenadyorov A. S. Aleksandr Sergeevich, Soloviev (Solovyev) A. A. Andrey Aleksandrovich, Ivanova N. M. Nina Mikhailovna, Zhulkov M. O. Maksim Olegovich, Chernyavskiy A. M. Aleksandr Mikhaylovich, Malashchenko V. V. Vladimir Vladimirovich, Khlusov I. A. Igor Albertovich
Summary:Title screen
Silicon- and oxygen-incorporated hydrogenated amorphous carbon films (a-C:H:SiOx) are deposited onto polypropylene substrates using plasma-assisted chemical vapor deposition to increase their antithrombogenicity and hemocompatibility. To increase the a-C:H:SiOx film adhesion to the polymer substrate, the latter is pretreated with argon or oxygen ions from the ion source with closed electron drift. The optimum conditions for the ion-beam treatment are determined by measurements of the surface wettability and chemical composition, the film morphology and adhesion. The adhesive properties are evaluated by the pull-off adhesion test. X-ray photoelectron spectroscopy shows the formation of new oxygen-containing functional groups after the exposure to both argon and oxygen ion beams. The highest film adhesion is observed for the substrate irradiated by oxygen ions, when the pull-off force increases from 3.4 to 24 kg/cm2. Various characterization techniques such as Fourier transform infrared spectroscopy, Raman spectroscopy, scanning electron microscopy are employed to study the a-C:H:SiOx film structure on a polymer substrate. In vitro investigation of platelet adhesion and cytotoxicity helps to evaluate the blood compatibility with the film. The a-C:H:SiOx film shows low thrombogenicity and no cytotoxic activity towards human leukocytes.
Режим доступа: по договору с организацией-держателем ресурса
Published: 2020
Subjects:
Online Access:https://doi.org/10.1016/j.surfcoat.2020.126132
Format: Electronic Book Chapter
KOHA link:https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=663362