Determination of the properties and loading efficiency of encapsulated BSA-FITC and dexamethasone for drug delivery systems; IOP Conference Series: Materials Science and Engineering; Vol. 597 : Prospects of Fundamental Sciences Development (PFSD-2019)

Determination of the properties and loading efficiency of encapsulated BSA-FITC and dexamethasone for drug delivery systems; IOP Conference Series: Materials Science and Engineering; Vol. 597 : Prospects of Fundamental Sciences Development (PFSD-2019)

书目详细资料
Parent link:IOP Conference Series: Materials Science and Engineering
Vol. 597 : Prospects of Fundamental Sciences Development (PFSD-2019).— 2019.— [012056, 6 p.]
企业作者: Национальный исследовательский Томский политехнический университет Исследовательская школа химических и биомедицинских технологий Научно-исследовательский центр "Физическое материаловедение и композитные материалы"
其他作者: Chudinova E. A. Ekaterina Aleksandrovna, Surmeneva M. A. Maria Alexandrovna, Koptyug A. V. Andrey Valentinovich, Sokolova V. Viktoriya, Primak O. Oleg, Bouckercha S., Epple M. Matthias, Surmenev R. A. Roman Anatolievich
总结:Title screen
In this work porous microparticles of calcium carbonate were synthesized with bovine serum albumin - fluorescein isothiocyanate conjugate (BSA-FITC) and dexamethasone, and then used for encapsulation in polymer microcapsules by means of layer-by-layer assembly (LbL). The properties of the obtained microcapsules were characterized by scanning electron microscopy, dynamic light scattering, infrared-, ultraviolet- and visible spectroscopy. According to the performed DLS measurements, an average hydrodynamic diameter ranged from 4 to 8 µm and zeta-potential for all types of capsules was determined as -18 and -21 mV. BSA-FITC was encapsulated using this approach yielded a loading efficiency of 49 % protein. This value calculated for dexamethasone was of 38%. The microcapsules filled with an encapsulated drug may find applications in the field of biotechnology, biochemistry, and medicine.
语言:英语
出版: 2019
主题:
электронный ресурс
труды учёных ТПУ
инкапсулированные фитоэкстракты
лекарства
在线阅读:https://doi.org/10.1088/1757-899X/597/1/012056
格式: 电子 本书章节
KOHA link:https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=662532

相似书籍

相似书籍