Cytotoxicity of New Ferulic-Acid Derivatives on Human Colon Carcinoma (HCT116) Cells; Pharmaceutical Chemistry Journal; Vol. 53, iss. 6

書誌詳細
Parent link:Pharmaceutical Chemistry Journal
Vol. 53, iss. 6.— 2019.— [P. 516-520]
団体著者: Национальный исследовательский Томский политехнический университет Инженерная школа новых производственных технологий Научно-образовательный центр Н. М. Кижнера
その他の著者: Bakholdina L. A. Lyubov Alekseevna, Markova A. A. Alyona Aleksandrovna, Khlebnikov A. I. Andrey Ivanovich, Sevodin V. P. Valery Pavlovich
要約:Title screen
A series of esters of ferulic acid and alcohols were synthesized and characterized structurally. All tested synthetic compounds were more cytotoxic against HCT116 cell line (human colon carcinoma) than ferulic acid. Benzyl and phenylethyl esters of ferulic acid were the most active compounds (IC50 = 0.0077 and 0.0065 g/L, respectively). Feruloylated wheat-bran oligosaccharides were less active than free ferulic acid against HCT116 tumor cells.
Режим доступа: по договору с организацией-держателем ресурса
言語:英語
出版事項: 2019
主題:
オンライン・アクセス:https://doi.org/10.1007/s11094-019-02030-y
フォーマット: 電子媒体 図書の章
KOHA link:https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=661890
その他の書誌記述
要約:Title screen
A series of esters of ferulic acid and alcohols were synthesized and characterized structurally. All tested synthetic compounds were more cytotoxic against HCT116 cell line (human colon carcinoma) than ferulic acid. Benzyl and phenylethyl esters of ferulic acid were the most active compounds (IC50 = 0.0077 and 0.0065 g/L, respectively). Feruloylated wheat-bran oligosaccharides were less active than free ferulic acid against HCT116 tumor cells.
Режим доступа: по договору с организацией-держателем ресурса
DOI:10.1007/s11094-019-02030-y