Cytotoxicity of New Ferulic-Acid Derivatives on Human Colon Carcinoma (HCT116) Cells

Cytotoxicity of New Ferulic-Acid Derivatives on Human Colon Carcinoma (HCT116) Cells

Bibliographic Details
Parent link:Pharmaceutical Chemistry Journal
Vol. 53, iss. 6.— 2019.— [P. 516-520]
Corporate Author: Национальный исследовательский Томский политехнический университет Инженерная школа новых производственных технологий Научно-образовательный центр Н. М. Кижнера
Other Authors: Bakholdina L. A. Lyubov Alekseevna, Markova A. A. Alyona Aleksandrovna, Khlebnikov A. I. Andrey Ivanovich, Sevodin V. P. Valery Pavlovich
Summary:Title screen
A series of esters of ferulic acid and alcohols were synthesized and characterized structurally. All tested synthetic compounds were more cytotoxic against HCT116 cell line (human colon carcinoma) than ferulic acid. Benzyl and phenylethyl esters of ferulic acid were the most active compounds (IC50 = 0.0077 and 0.0065 g/L, respectively). Feruloylated wheat-bran oligosaccharides were less active than free ferulic acid against HCT116 tumor cells.
Режим доступа: по договору с организацией-держателем ресурса
Published: 2019
Subjects:
электронный ресурс
труды учёных ТПУ
feruloyl oligosaccharides
synthesis
ferulic-acid esters
cytotoxicity
HCT116 human colon carcinoma
синтез
феруловая кислота
эфиры
цитотоксичность
Online Access:https://doi.org/10.1007/s11094-019-02030-y
Format: Electronic Book Chapter
KOHA link:https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=661890

Internet

https://doi.org/10.1007/s11094-019-02030-y

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