“Solvent/non-solvent” treatment as a method for non-covalent immobilization of gelatin on the surface of poly(l-lactic acid) electrospun scaffolds
| Parent link: | Colloids and Surfaces B: Biointerfaces Vol. 177.— 2019.— [P. 137-140] |
|---|---|
| निगमित लेखकों: | , |
| अन्य लेखक: | , , , , , , , , |
| सारांश: | Title screen In the present study, we report a simple and efficient method of gelatin immobilization on the surface of PLA electrospun fibers using pre-treatment with a mixture of toluene and ethanol allowing to form swelled surface layer followed by gelatin adsorption from its solution in PBS. Our results demonstrate that gelatin immobilization leads to a decrease in the water contact angle from 120° to 0°, enhances scaffold strength up to 50%, and doubles the number of adhered cells and their average area. We observed that the maximum amount of gelatin (0.07?±?0.01?mg per cm3 of the scaffold) was immobilized during the first five minutes of exposure to the gelatin solution. Modified scaffolds demonstrated increased strength. Режим доступа: по договору с организацией-держателем ресурса |
| प्रकाशित: |
2019
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| विषय: | |
| ऑनलाइन पहुंच: | https://doi.org/10.1016/j.colsurfb.2019.01.060 |
| स्वरूप: | इलेक्ट्रोनिक पुस्तक अध्याय |
| KOHA link: | https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=659633 |
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