“Solvent/non-solvent” treatment as a method for non-covalent immobilization of gelatin on the surface of poly(l-lactic acid) electrospun scaffolds
| Parent link: | Colloids and Surfaces B: Biointerfaces Vol. 177.— 2019.— [P. 137-140] |
|---|---|
| Egile korporatiboa: | , |
| Beste egile batzuk: | , , , , , , , , |
| Gaia: | Title screen In the present study, we report a simple and efficient method of gelatin immobilization on the surface of PLA electrospun fibers using pre-treatment with a mixture of toluene and ethanol allowing to form swelled surface layer followed by gelatin adsorption from its solution in PBS. Our results demonstrate that gelatin immobilization leads to a decrease in the water contact angle from 120° to 0°, enhances scaffold strength up to 50%, and doubles the number of adhered cells and their average area. We observed that the maximum amount of gelatin (0.07?±?0.01?mg per cm3 of the scaffold) was immobilized during the first five minutes of exposure to the gelatin solution. Modified scaffolds demonstrated increased strength. Режим доступа: по договору с организацией-держателем ресурса |
| Hizkuntza: | ingelesa |
| Argitaratua: |
2019
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| Gaiak: | |
| Sarrera elektronikoa: | https://doi.org/10.1016/j.colsurfb.2019.01.060 |
| Formatua: | Baliabide elektronikoa Liburu kapitulua |
| KOHA link: | https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=659633 |
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| 200 | 1 | |a “Solvent/non-solvent” treatment as a method for non-covalent immobilization of gelatin on the surface of poly(l-lactic acid) electrospun scaffolds |f S. I. Goreninsky, R. O. Gulyaev, K. S. Stankevich [et al.] | |
| 203 | |a Text |c electronic | ||
| 300 | |a Title screen | ||
| 320 | |a [References: 19 tit.] | ||
| 330 | |a In the present study, we report a simple and efficient method of gelatin immobilization on the surface of PLA electrospun fibers using pre-treatment with a mixture of toluene and ethanol allowing to form swelled surface layer followed by gelatin adsorption from its solution in PBS. Our results demonstrate that gelatin immobilization leads to a decrease in the water contact angle from 120° to 0°, enhances scaffold strength up to 50%, and doubles the number of adhered cells and their average area. We observed that the maximum amount of gelatin (0.07?±?0.01?mg per cm3 of the scaffold) was immobilized during the first five minutes of exposure to the gelatin solution. Modified scaffolds demonstrated increased strength. | ||
| 333 | |a Режим доступа: по договору с организацией-держателем ресурса | ||
| 461 | |t Colloids and Surfaces B: Biointerfaces | ||
| 463 | |t Vol. 177 |v [P. 137-140] |d 2019 | ||
| 610 | 1 | |a электронный ресурс | |
| 610 | 1 | |a труды учёных ТПУ | |
| 610 | 1 | |a polylactic acid | |
| 610 | 1 | |a gelatin | |
| 610 | 1 | |a electrospun scaffolds | |
| 610 | 1 | |a surface modification | |
| 610 | 1 | |a желатин | |
| 610 | 1 | |a поверхностный слой | |
| 610 | 1 | |a строительные леса | |
| 701 | 1 | |a Goreninsky |b S. I. |c chemist |c engineer of Tomsk Polytechnic University |f 1993- |g Semen Igorevich |3 (RuTPU)RU\TPU\pers\40080 | |
| 701 | 1 | |a Gulyaev |b R. O. |c chemical engineer |c Research Engineer of Tomsk Polytechnic University |f 1995- |g Roman Olegovich |3 (RuTPU)RU\TPU\pers\47540 | |
| 701 | 1 | |a Stankevich |b K. S. |c Physicist |c Engineer Tomsk Polytechnic University |f 1992- |g Ksenia Sergeevnahttps://online.sberbank.ru/CSAFront/index.do |3 (RuTPU)RU\TPU\pers\37546 | |
| 701 | 1 | |a Danilenko |b N. V. |c chemical engineer |c Research Engineer, Tomsk Polytechnic University |f 1992- |g Nadezhda Viktorovna |3 (RuTPU)RU\TPU\pers\37547 |9 20416 | |
| 701 | 1 | |a Bolbasov |b E. N. |c physicist |c Senior Researcher at Tomsk Polytechnic University, Candidate of Technical Sciences |f 1981- |g Evgeny Nikolaevich |3 (RuTPU)RU\TPU\pers\30857 |9 15103 | |
| 701 | 1 | |a Golovkin |b A. S. |g Aleksey Sergeevich | |
| 701 | 1 | |a Mishanin |b A. I. |g Aleksandr | |
| 701 | 1 | |a Filimonov |b V. D. |c Russian chemist |c Professor of the TPU |f 1945- |g Viktor Dmitrievich |3 (RuTPU)RU\TPU\pers\26423 |9 12127 | |
| 701 | 1 | |a Tverdokhlebov |b S. I. |c physicist |c Associate Professor of Tomsk Polytechnic University, Candidate of physical and mathematical science |f 1961- |g Sergei Ivanovich |3 (RuTPU)RU\TPU\pers\30855 |9 15101 | |
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