Voltammetric Sensing System for the Detection of Cholesterol Based on the Ni-Bisurea-Pyrographite Composite

Bibliographic Details
Parent link:Key Engineering Materials: Scientific Journal
Vol. 769 : High Technology: Research and Applications (HTRA 2017).— 2018.— [250-255]
Corporate Authors: Национальный исследовательский Томский политехнический университет Школа базовой инженерной подготовки Отделение естественных наук, Национальный исследовательский Томский политехнический университет Инженерная школа природных ресурсов Отделение химической инженерии
Other Authors: Lukina A. A. Anastasia, Ismailov D. V. Daniar, Ilyin A. P. Aleksandr Petrovich, Derina K. V. Kseniya Vladimirovna, Korotkova E. I. Elena Ivanovna
Summary:Title screen
Cholesterol plays a crucial role in the human body. High cholesterol level in blood is a marker of CVDs. Therefore, cholesterol determination techniques are necessary for clinical practice. Currently used cholesterol determination techniques involve enzymes or expensive and complicated equipment. Electrochemical techniques are widely spread in test-systems and sensors construction. Novel modification procedure for enzymeless cholesterol determination is suggested in this study. The electrochemical behavior of cholesterol on modified electrode was studied with the usage of cyclic and differential pulse voltammetry. Obtained concentration range is linear from 0.1 up to 100 mM a conditions close to physiological (pH=6.86) with a quantification limit of 0.01 mM. Besides, the electrode surface morphology and pH-effect were studied. The developed technique is promising for the rapid determination of total cholesterol in blood.
Режим доступа: по договору с организацией-держателем ресурса
Published: 2018
Subjects:
Online Access:https://doi.org/10.4028/www.scientific.net/KEM.769.250
Format: Electronic Book Chapter
KOHA link:https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=658647