Synthesis and biological activity of hydrazones of o- and p-hydroxybenzoic acids. Spatial structure of 5-Bromo-2-hydroxybenzylidene-4-hydroxybenzohydrazide; Russian Journal of General Chemistry; Vol. 87, iss. 10

Synthesis and biological activity of hydrazones of o- and p-hydroxybenzoic acids. Spatial structure of 5-Bromo-2-hydroxybenzylidene-4-hydroxybenzohydrazide

Bibliographic Details
Parent link:Russian Journal of General Chemistry.— , 2001-
Vol. 87, iss. 10.— 2017.— [P. 2299–2306]
Corporate Authors: Национальный исследовательский Томский политехнический университет (ТПУ) Управление проректора по научной работе и инновациям (НРиИ) Центр RASA в Томске Лаборатория изучения механизмов нейропротекции (Лаб. ИМН), Национальный исследовательский Томский политехнический университет (ТПУ) Институт физики высоких технологий (ИФВТ) Кафедра биотехнологии и органической химии (БИОХ)
Other Authors: Nurkenov O. A., Satpaeva Zh. B., Shchepyotkin I. A. Igor Aleksandrovich, Khlebnikov A. I. Andrey Ivanovich, Turdybekov K. M., Seylkhanov T. M., Fazylov S. D.
Summary:Title screen
A series of hydrazones based on hydrazides of o- and p-hydroxybenzoic acids have been prepared. N-(5-Bromo-2-hydroxybenzylidene)-4-hydroxybenzohydrazide has been studied by X-ray diffraction analysis; its molecule forms hydrogen bond with a solvating ethanol molecule. Biological activity of the synthesized hydrazones towards cathepsin Е and(or) elastase of human neutrophils has been determined.
Режим доступа: по договору с организацией-держателем ресурса
Language:English
Published: 2017
Subjects:
электронный ресурс
труды учёных ТПУ
гидразоны
гидразиды
гидроксибензойная кислота
катепсины
нейтрофильная эластаза
молекулярная стыковка
hydrazone
hydroxybenzoic acid hydrazide
cathepsin Е
neutrophil elastase
molecular docking
Online Access:http://dx.doi.org/10.1134/S1070363217100097
Format: Electronic Book Chapter
KOHA link:https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=657688
Description
Summary:Title screen
A series of hydrazones based on hydrazides of o- and p-hydroxybenzoic acids have been prepared. N-(5-Bromo-2-hydroxybenzylidene)-4-hydroxybenzohydrazide has been studied by X-ray diffraction analysis; its molecule forms hydrogen bond with a solvating ethanol molecule. Biological activity of the synthesized hydrazones towards cathepsin Е and(or) elastase of human neutrophils has been determined.
Режим доступа: по договору с организацией-держателем ресурса
DOI:10.1134/S1070363217100097

Similar Items