A Novel Glycosyl Donor with a Triisopropylsilyl Nonparticipating Group in Benzyl-Free Stereoselective 1,2-cis-Galactosylation; Synlett; Vol. 28, iss. 13

A Novel Glycosyl Donor with a Triisopropylsilyl Nonparticipating Group in Benzyl-Free Stereoselective 1,2-cis-Galactosylation; Synlett; Vol. 28, iss. 13

Bibliographic Details
Parent link:Synlett
Vol. 28, iss. 13.— 2017.— [P. 1608-1613]
Corporate Author: Национальный исследовательский Томский политехнический университет (ТПУ) Институт физики высоких технологий (ИФВТ) Кафедра биотехнологии и органической химии (БИОХ)
Other Authors: Abronina P. I. Polina Igorevna, Zinin A. I. Aleksandr Ivanovich, Malysheva N. N. Nelli Nikolaevna, Stepanova E. V. Elena Vladimirovna, Chizhov A. O. Aleksandr Olegovich, Torgov V. I. Vladimir Igorevich, Kononov L. O. Leonid Olegovich
Summary:Title screen
A novel glycosyl donor with a triisopropylsilyl (TIPS) nonparticipating group at O-2 is introduced for use in 1,2-cis-galactosylation. Coupling the 2-O-TIPS-substituted thiogalactoside donor with a series of mono- and disaccharide glycosyl acceptors was found to lead exclusively to a-linked oligosaccharides. The observed exceptionally high a-selectivity was interpreted in terms of conformational changes in the glycosyl cation induced by the bulky 2-O-TIPS group.
Language:English
Published: 2017
Subjects:
электронный ресурс
труды учёных ТПУ
glycosylation
stereoselectivity
stereoselective synthesis
conformation
protecting groups
triisopropylsilyl group
4-(3-chloropropoxy)phenyl glycosides
стереоселективный синтез
конформация
защитные группы
гликозилирование
стереоселективность
фенилгликозиды
Online Access:http://earchive.tpu.ru/handle/11683/64909
https://doi.org/10.1055/s-0036-1589028
Format: Electronic Book Chapter
KOHA link:https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=656357

Internet

http://earchive.tpu.ru/handle/11683/64909
https://doi.org/10.1055/s-0036-1589028

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