Osteoinductive composite coatings for flexible intramedullary nails

Osteoinductive composite coatings for flexible intramedullary nails

Bibliographic Details
Parent link:	Materials Science and Engineering: C.— , 1993- Vol. 75.— 2017.— [P. 207–220]
Corporate Author:	Национальный исследовательский Томский политехнический университет (ТПУ) Физико-технический институт (ФТИ) Кафедра экспериментальной физики (ЭФ)
Other Authors:	Bolbasov E. N. Evgeny Nikolaevich, Popkov A. V. Arnold Vasiljevich, Popkov D. A. Dmitry Arnoldovich, Gorbach E. N. Elena Nikolaevna, Khlusov I. A. Igor Albertovich, Golovkin A. S. Aleksey Sergeevich, Sinev A. M. Andrey Mansurovich, Buznik V. M. Vyacheslav Mikhaylovich, Tverdokhlebov S. I. Sergei Ivanovich, Anissimov Y. G. Yuri
Summary:	Title screen This work presents composite coatings based on a copolymer of vinylidene fluoride with tetrafluoroethylene (VDF-TeFE) and hydroxyapatite (HA) for flexible intramedullary nails (FIN). The effect of the proportion of VDF-TeFE (100-25% wt.) on physicochemical and biological properties of the composite coatings was investigated. It was shown that a decrease of VDF-TeFE in the coating hinders its crystallization in β and γ forms which have piezoelectric properties. The decrease also reduces an adhesive strength to 9.9 ± 2.4 MPa and a relative elongation to 5.9 ± 1.2%, but results in increased osteogenesis. It was demonstrated that the composite coatings with 35% VDF-TeFE has the required combination of physicochemical properties and osteogenic activity. Comparative studies of composite coatings (35% VDF-TeFE) and calcium phosphate coatings produced using micro-arc oxidation, demonstrated comparable results for strength of bonding of these FINs with trabecular bones (~530 MPa). It was hypothesized that the high osteoinductive properties of the composite coatings are due to their piezoelectric properties. Режим доступа: по договору с организацией-держателем ресурса
Published:	2017
Subjects:	электронный ресурс труды учёных ТПУ hydroxyapatite piezoelectric сополимеры гидроксиапатиты остеоиндуктивные покрытия композиционные покрытия
Online Access:	http://dx.doi.org/10.1016/j.msec.2017.02.073
Format:	Electronic Book Chapter
KOHA link:	https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=654565

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