Osteoinductive composite coatings for flexible intramedullary nails
| Parent link: | Materials Science and Engineering: C.— , 1993- Vol. 75.— 2017.— [P. 207–220] |
|---|---|
| Corporate Author: | |
| Other Authors: | , , , , , , , , , |
| Summary: | Title screen This work presents composite coatings based on a copolymer of vinylidene fluoride with tetrafluoroethylene (VDF-TeFE) and hydroxyapatite (HA) for flexible intramedullary nails (FIN). The effect of the proportion of VDF-TeFE (100-25% wt.) on physicochemical and biological properties of the composite coatings was investigated. It was shown that a decrease of VDF-TeFE in the coating hinders its crystallization in β and γ forms which have piezoelectric properties. The decrease also reduces an adhesive strength to 9.9 ± 2.4 MPa and a relative elongation to 5.9 ± 1.2%, but results in increased osteogenesis. It was demonstrated that the composite coatings with 35% VDF-TeFE has the required combination of physicochemical properties and osteogenic activity. Comparative studies of composite coatings (35% VDF-TeFE) and calcium phosphate coatings produced using micro-arc oxidation, demonstrated comparable results for strength of bonding of these FINs with trabecular bones (~530 MPa). It was hypothesized that the high osteoinductive properties of the composite coatings are due to their piezoelectric properties. Режим доступа: по договору с организацией-держателем ресурса |
| Published: |
2017
|
| Subjects: | |
| Online Access: | http://dx.doi.org/10.1016/j.msec.2017.02.073 |
| Format: | Electronic Book Chapter |
| KOHA link: | https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=654565 |