Osteoinductive composite coatings for flexible intramedullary nails
| Parent link: | Materials Science and Engineering: C.— , 1993- Vol. 75.— 2017.— [P. 207–220] |
|---|---|
| Körperschaft: | |
| Weitere Verfasser: | , , , , , , , , , |
| Zusammenfassung: | Title screen This work presents composite coatings based on a copolymer of vinylidene fluoride with tetrafluoroethylene (VDF-TeFE) and hydroxyapatite (HA) for flexible intramedullary nails (FIN). The effect of the proportion of VDF-TeFE (100-25% wt.) on physicochemical and biological properties of the composite coatings was investigated. It was shown that a decrease of VDF-TeFE in the coating hinders its crystallization in β and γ forms which have piezoelectric properties. The decrease also reduces an adhesive strength to 9.9 ± 2.4 MPa and a relative elongation to 5.9 ± 1.2%, but results in increased osteogenesis. It was demonstrated that the composite coatings with 35% VDF-TeFE has the required combination of physicochemical properties and osteogenic activity. Comparative studies of composite coatings (35% VDF-TeFE) and calcium phosphate coatings produced using micro-arc oxidation, demonstrated comparable results for strength of bonding of these FINs with trabecular bones (~530 MPa). It was hypothesized that the high osteoinductive properties of the composite coatings are due to their piezoelectric properties. Режим доступа: по договору с организацией-держателем ресурса |
| Sprache: | Englisch |
| Veröffentlicht: |
2017
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| Schlagworte: | |
| Online-Zugang: | http://dx.doi.org/10.1016/j.msec.2017.02.073 |
| Format: | Elektronisch Buchkapitel |
| KOHA link: | https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=654565 |
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| 200 | 1 | |a Osteoinductive composite coatings for flexible intramedullary nails |f E. N. Bolbasov [et al.] | |
| 203 | |a Text |c electronic | ||
| 300 | |a Title screen | ||
| 320 | |a [References: p. 218-220 (118 tit.)] | ||
| 330 | |a This work presents composite coatings based on a copolymer of vinylidene fluoride with tetrafluoroethylene (VDF-TeFE) and hydroxyapatite (HA) for flexible intramedullary nails (FIN). The effect of the proportion of VDF-TeFE (100-25% wt.) on physicochemical and biological properties of the composite coatings was investigated. It was shown that a decrease of VDF-TeFE in the coating hinders its crystallization in β and γ forms which have piezoelectric properties. The decrease also reduces an adhesive strength to 9.9 ± 2.4 MPa and a relative elongation to 5.9 ± 1.2%, but results in increased osteogenesis. It was demonstrated that the composite coatings with 35% VDF-TeFE has the required combination of physicochemical properties and osteogenic activity. Comparative studies of composite coatings (35% VDF-TeFE) and calcium phosphate coatings produced using micro-arc oxidation, demonstrated comparable results for strength of bonding of these FINs with trabecular bones (~530 MPa). It was hypothesized that the high osteoinductive properties of the composite coatings are due to their piezoelectric properties. | ||
| 333 | |a Режим доступа: по договору с организацией-держателем ресурса | ||
| 461 | |t Materials Science and Engineering: C |d 1993- | ||
| 463 | |t Vol. 75 |v [P. 207–220] |d 2017 | ||
| 610 | 1 | |a электронный ресурс | |
| 610 | 1 | |a труды учёных ТПУ | |
| 610 | 1 | |a hydroxyapatite | |
| 610 | 1 | |a piezoelectric | |
| 610 | 1 | |a сополимеры | |
| 610 | 1 | |a гидроксиапатиты | |
| 610 | 1 | |a остеоиндуктивные покрытия | |
| 610 | 1 | |a композиционные покрытия | |
| 701 | 1 | |a Bolbasov |b E. N. |c physicist |c Senior Researcher at Tomsk Polytechnic University, Candidate of Technical Sciences |f 1981- |g Evgeny Nikolaevich |3 (RuTPU)RU\TPU\pers\30857 |9 15103 | |
| 701 | 1 | |a Popkov |b A. V. |g Arnold Vasiljevich | |
| 701 | 1 | |a Popkov |b D. A. |g Dmitry Arnoldovich | |
| 701 | 1 | |a Gorbach |b E. N. |g Elena Nikolaevna | |
| 701 | 1 | |a Khlusov |b I. A. |c biophysicist |c Professor of Tomsk Polytechnic University, doctor of medical Sciences |f 1963- |g Igor Albertovich |3 (RuTPU)RU\TPU\pers\34907 |9 18225 | |
| 701 | 1 | |a Golovkin |b A. S. |g Aleksey Sergeevich | |
| 701 | 1 | |a Sinev |b A. M. |g Andrey Mansurovich | |
| 701 | 1 | |a Buznik |b V. M. |g Vyacheslav Mikhaylovich | |
| 701 | 1 | |a Tverdokhlebov |b S. I. |c physicist |c Associate Professor of Tomsk Polytechnic University, Candidate of physical and mathematical science |f 1961- |g Sergei Ivanovich |3 (RuTPU)RU\TPU\pers\30855 |9 15101 | |
| 701 | 1 | |a Anissimov |b Y. G. |g Yuri | |
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