Acidic properties of N-hetarylacetic acids and inductive constants of N-hetaryl substituents

Bibliographic Details
Parent link:Chemistry of Heterocyclic Compounds
Vol. 19, iss. 3.— 1983.— [P. 300-303]
Other Authors: Filippova T. A., Sukhoroslova M. M., Lopatinskii V. P., Filimonov V. D. Viktor Dmitrievich
Summary:Title screen
The inductive constants of the corresponding heterocyclic fragments were calculated on the basis of data on the pKa values obtained by potentiometric titration of derivatives of indole, carbazole, 3-methylcarbazole, tetrahydrocarbazole, 6-methyltetrahydrocarbazole, and phenothiazine. The σRoconstant of the 9-carbazolyl group was also calculated. The enthalpy and entropy of acidic dissociation were calculated from data on the effect of the temperature on the pKa of 9-carbazolylacetic acid. It is shown that the entropy contribution to the free energy of dissociation of 9-carbazolylacetic acid predominates.
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Published: 1983
Subjects:
Online Access:http://dx.doi.org/10.1007/BF00513265
Format: Electronic Book Chapter
KOHA link:https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=654464