Synthesis and Properties of Iron-Based Magnetic Nanoparticles

Bibliographic Details
Parent link:Key Engineering Materials: Scientific Journal
Vol. 712 : Advanced Materials for Technical and Medical Purpose (AMTMP 2016).— 2016.— [P. 282-287]
Main Author: Sashko N. Nikita
Corporate Author: Национальный исследовательский Томский политехнический университет (ТПУ) Институт физики высоких технологий (ИФВТ) Кафедра общей химии и химической технологии (ОХХТ)
Other Authors: Vaytulevich (Vaitulevich) E. A. Elena Anatolievna, Yurmazova T. A. Tatyana Aleksandrovna
Summary:Title screen
We have obtained magnetite nanoparticles (MNP) by using chemical coprecipitation of Fe{2+} and Fe{3+} in water solution. The size of these particles was less than 9 nm, and they possessed corresponding physical and chemical properties. Citric acid was used to stabilize magnetite particles suspension. The acid was affixed to the surface of the particles by adding it in fresh MNP solution during synthesis. Affixing carboxyl groups on the surface of MNP not only does improve particles' dispersion in solvent, but also allows adding further modifications to their surface. The properties of the particles' microstructure and morphology were determined with X-Ray diffraction (XRD) and transmission electron microscopy (TEM), whereas their magnetic properties were determined by means of automated pulse magnetic field analysis equipment. Magnetic measurements have shown that saturation magnetization was 94 emu/g with nanoparticles being at room temperature. We have also researched possible application of these particles as drug carriers by determining doxorubicin sorption capacity on the surface of MNPs. These MNPs have proven to have perspective ability to be a magnetic field-controlled carrier for cancer-treating drugs. The obtained particles can also potentially be used as a contrast medium for MRI.
Режим доступа: по договору с организацией-держателем ресурса
Published: 2016
Series:Materials and Technologies for Biomedical Application and Environmental Engineering
Subjects:
Online Access:http://dx.doi.org/10.4028/www.scientific.net/KEM.712.282
Format: Electronic Book Chapter
KOHA link:https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=651346