Investigation of new nsaids for the treatment of inflammatory diseases of kidney and urinary tract; Jurnal Teknologi; Vol. 78, iss. 5-6

Detalhes bibliográficos
Parent link:Jurnal Teknologi.— , 1977-
Vol. 78, iss. 5-6.— 2016.— [P. 89-92]
Autor Corporativo: Национальный исследовательский Томский политехнический университет Институт физики высоких технологий Лаборатория № 1
Outros Autores: Murashko T. O. Tatjyana Olegovna, Ivanov A. A. Aleksey Alekseevich, Smirnov I. V. Ivan Vladimirovich, Bondarev A. A. Aleksandr Aleksandrovich, Nemtsev A. O. Aleksey Olegovich, Udut V. V. Vladimir Vasiljevich
Resumo:Title screen
Non-steroidal anti-inflammatory drugs (NSAIDs) are widely used in the world, primarily due to their high efficiency for the treatment of inflammatory induced pain syndrome. The main feature of NSAIDs is a combination of anti-inflammatory, analgesic, antipyretic, and anticoagulant properties. However, their long-term use is associated with side effects in the gastrointestinal tract including peptic ulcers and other. We developed and synthesized molecule of methyl (4-О-β-glucopyranosyloxy)-benzoic acid. The anti-inflammatory effect of methyl (4-О-β-glucopyranosyloxy)-benzoic acid evaluated using the carrageenan-induced hindpaw edema model. The study shows that the intragastrically administration of test substance to animals reduces inflammatory process.
Режим доступа: по договору с организацией-держателем ресурса
Idioma:inglês
Publicado em: 2016
Assuntos:
Acesso em linha:http://dx.doi.org/10.11113/jt.v78.8643
Formato: MixedMaterials Recurso Eletrônico Capítulo de Livro
KOHA link:https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=651033

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330 |a Non-steroidal anti-inflammatory drugs (NSAIDs) are widely used in the world, primarily due to their high efficiency for the treatment of inflammatory induced pain syndrome. The main feature of NSAIDs is a combination of anti-inflammatory, analgesic, antipyretic, and anticoagulant properties. However, their long-term use is associated with side effects in the gastrointestinal tract including peptic ulcers and other. We developed and synthesized molecule of methyl (4-О-β-glucopyranosyloxy)-benzoic acid. The anti-inflammatory effect of methyl (4-О-β-glucopyranosyloxy)-benzoic acid evaluated using the carrageenan-induced hindpaw edema model. The study shows that the intragastrically administration of test substance to animals reduces inflammatory process. 
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701 1 |a Ivanov  |b A. A.  |c specialist in the field of Electrophysics  |c engineer of Tomsk Polytechnic University  |f 1990-  |g Aleksey Alekseevich  |3 (RuTPU)RU\TPU\pers\35679  |9 18840 
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701 1 |a Udut  |b V. V.  |g Vladimir Vasiljevich 
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