Investigation of new nsaids for the treatment of inflammatory diseases of kidney and urinary tract

Bibliographic Details
Parent link:Jurnal Teknologi.— , 1977-
Vol. 78, iss. 5-6.— 2016.— [P. 89-92]
Corporate Author: Национальный исследовательский Томский политехнический университет Институт физики высоких технологий Лаборатория № 1
Other Authors: Murashko T. O. Tatjyana Olegovna, Ivanov A. A. Aleksey Alekseevich, Smirnov I. V. Ivan Vladimirovich, Bondarev A. A. Aleksandr Aleksandrovich, Nemtsev A. O. Aleksey Olegovich, Udut V. V. Vladimir Vasiljevich
Summary:Title screen
Non-steroidal anti-inflammatory drugs (NSAIDs) are widely used in the world, primarily due to their high efficiency for the treatment of inflammatory induced pain syndrome. The main feature of NSAIDs is a combination of anti-inflammatory, analgesic, antipyretic, and anticoagulant properties. However, their long-term use is associated with side effects in the gastrointestinal tract including peptic ulcers and other. We developed and synthesized molecule of methyl (4-О-β-glucopyranosyloxy)-benzoic acid. The anti-inflammatory effect of methyl (4-О-β-glucopyranosyloxy)-benzoic acid evaluated using the carrageenan-induced hindpaw edema model. The study shows that the intragastrically administration of test substance to animals reduces inflammatory process.
Режим доступа: по договору с организацией-держателем ресурса
Published: 2016
Subjects:
Online Access:http://dx.doi.org/10.11113/jt.v78.8643
Format: Electronic Book Chapter
KOHA link:https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=651033