pHLIP-modified magnetic nanoparticles for targeting acidic diseased tissue; RSC Advances; Vol. 6, iss. 65

PHLIP-modified magnetic nanoparticles for targeting acidic diseased tissue; RSC Advances; Vol. 6, iss. 65

Dettagli Bibliografici
Parent link:	RSC Advances.— , 2011- Vol. 6, iss. 65.— 2016.— [P. 60196-60199]
Ente Autore:	Национальный исследовательский Томский политехнический университет Институт физики высоких технологий Кафедра биотехнологии и органической химии
Altri autori:	Demin A. M. Aleksandr Mikhaylovich, Pershina A. G. Aleksandra Gennadievna, Nevskaya K. V. Ksenia Vladimirovna, Efimova L. V. Lina Viktorovna, Shchegoleva N. N. Nina Nikiforovna, Uymin A. M. Alexandr Michaylovitch, Kuznetsov D. K. Dmitrii Konstantinovich, Shur V. Ya. Vladimir Yakovlevich, Krasnov V. P. Viktor Pavlovich, Ogorodova L. M. Lyudmila Mikhaylovna
Riassunto:	Title screen Covalent immobilization of a pH-low insertion peptide (pHLIP) onto Fe3O4 magnetic nanoparticles was carried out resulting in the formation of MRI-visible materials able to specifically accumulate in acidic damaged tissue. The pH-dependent pHLIP-mediated binding of the obtained nanoconjugates to cells in acidic environment was demonstrated on HTC cells in vitro and in a mouse LLC tumour model in vivo. Режим доступа: по договору с организацией-держателем ресурса
Lingua:	inglese
Pubblicazione:	2016
Soggetti:	электронный ресурс труды учёных ТПУ
Accesso online:	http://dx.doi.org/10.1039/C6RA13178F
Natura:	Elettronico Capitolo di libro
KOHA link:	https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=650722

Accesso online

http://dx.doi.org/10.1039/C6RA13178F