pHLIP-modified magnetic nanoparticles for targeting acidic diseased tissue; RSC Advances; Vol. 6, iss. 65

PHLIP-modified magnetic nanoparticles for targeting acidic diseased tissue; RSC Advances; Vol. 6, iss. 65

Podrobná bibliografie
Parent link:	RSC Advances.— , 2011- Vol. 6, iss. 65.— 2016.— [P. 60196-60199]
Korporativní autor:	Национальный исследовательский Томский политехнический университет Институт физики высоких технологий Кафедра биотехнологии и органической химии
Další autoři:	Demin A. M. Aleksandr Mikhaylovich, Pershina A. G. Aleksandra Gennadievna, Nevskaya K. V. Ksenia Vladimirovna, Efimova L. V. Lina Viktorovna, Shchegoleva N. N. Nina Nikiforovna, Uymin A. M. Alexandr Michaylovitch, Kuznetsov D. K. Dmitrii Konstantinovich, Shur V. Ya. Vladimir Yakovlevich, Krasnov V. P. Viktor Pavlovich, Ogorodova L. M. Lyudmila Mikhaylovna
Shrnutí:	Title screen Covalent immobilization of a pH-low insertion peptide (pHLIP) onto Fe3O4 magnetic nanoparticles was carried out resulting in the formation of MRI-visible materials able to specifically accumulate in acidic damaged tissue. The pH-dependent pHLIP-mediated binding of the obtained nanoconjugates to cells in acidic environment was demonstrated on HTC cells in vitro and in a mouse LLC tumour model in vivo. Режим доступа: по договору с организацией-держателем ресурса
Jazyk:	angličtina
Vydáno:	2016
Témata:	электронный ресурс труды учёных ТПУ
On-line přístup:	http://dx.doi.org/10.1039/C6RA13178F
Médium:	Elektronický zdroj Kapitola
KOHA link:	https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=650722

Internet

http://dx.doi.org/10.1039/C6RA13178F