pHLIP-modified magnetic nanoparticles for targeting acidic diseased tissue; RSC Advances; Vol. 6, iss. 65

PHLIP-modified magnetic nanoparticles for targeting acidic diseased tissue; RSC Advances; Vol. 6, iss. 65

Opis bibliograficzny
Parent link:	RSC Advances.— , 2011- Vol. 6, iss. 65.— 2016.— [P. 60196-60199]
Korporacja:	Национальный исследовательский Томский политехнический университет Институт физики высоких технологий Кафедра биотехнологии и органической химии
Kolejni autorzy:	Demin A. M. Aleksandr Mikhaylovich, Pershina A. G. Aleksandra Gennadievna, Nevskaya K. V. Ksenia Vladimirovna, Efimova L. V. Lina Viktorovna, Shchegoleva N. N. Nina Nikiforovna, Uymin A. M. Alexandr Michaylovitch, Kuznetsov D. K. Dmitrii Konstantinovich, Shur V. Ya. Vladimir Yakovlevich, Krasnov V. P. Viktor Pavlovich, Ogorodova L. M. Lyudmila Mikhaylovna
Streszczenie:	Title screen Covalent immobilization of a pH-low insertion peptide (pHLIP) onto Fe3O4 magnetic nanoparticles was carried out resulting in the formation of MRI-visible materials able to specifically accumulate in acidic damaged tissue. The pH-dependent pHLIP-mediated binding of the obtained nanoconjugates to cells in acidic environment was demonstrated on HTC cells in vitro and in a mouse LLC tumour model in vivo. Режим доступа: по договору с организацией-держателем ресурса
Język:	angielski
Wydane:	2016
Hasła przedmiotowe:	электронный ресурс труды учёных ТПУ
Dostęp online:	http://dx.doi.org/10.1039/C6RA13178F
Format:	Elektroniczne Rozdział
KOHA link:	https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=650722

Internet

http://dx.doi.org/10.1039/C6RA13178F