PHLIP-modified magnetic nanoparticles for targeting acidic diseased tissue; RSC Advances; Vol. 6, iss. 65
| Parent link: | RSC Advances.— , 2011- Vol. 6, iss. 65.— 2016.— [P. 60196-60199] |
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| Autor kompanije: | |
| Daljnji autori: | , , , , , , , , , |
| Sažetak: | Title screen Covalent immobilization of a pH-low insertion peptide (pHLIP) onto Fe3O4 magnetic nanoparticles was carried out resulting in the formation of MRI-visible materials able to specifically accumulate in acidic damaged tissue. The pH-dependent pHLIP-mediated binding of the obtained nanoconjugates to cells in acidic environment was demonstrated on HTC cells in vitro and in a mouse LLC tumour model in vivo. Режим доступа: по договору с организацией-держателем ресурса |
| Jezik: | engleski |
| Izdano: |
2016
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| Teme: | |
| Online pristup: | http://dx.doi.org/10.1039/C6RA13178F |
| Format: | Elektronički Poglavlje knjige |
| KOHA link: | https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=650722 |
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| 200 | 1 | |a pHLIP-modified magnetic nanoparticles for targeting acidic diseased tissue |f A. M. Demin [et al.] | |
| 203 | |a Text |c electronic | ||
| 300 | |a Title screen | ||
| 330 | |a Covalent immobilization of a pH-low insertion peptide (pHLIP) onto Fe3O4 magnetic nanoparticles was carried out resulting in the formation of MRI-visible materials able to specifically accumulate in acidic damaged tissue. The pH-dependent pHLIP-mediated binding of the obtained nanoconjugates to cells in acidic environment was demonstrated on HTC cells in vitro and in a mouse LLC tumour model in vivo. | ||
| 333 | |a Режим доступа: по договору с организацией-держателем ресурса | ||
| 461 | |t RSC Advances |d 2011- | ||
| 463 | |t Vol. 6, iss. 65 |v [P. 60196-60199] |d 2016 | ||
| 610 | 1 | |a электронный ресурс | |
| 610 | 1 | |a труды учёных ТПУ | |
| 701 | 1 | |a Demin |b A. M. |g Aleksandr Mikhaylovich | |
| 701 | 1 | |a Pershina |b A. G. |c biologist |c Associate Professor of Tomsk Polytechnic University, Candidate of biological sciences |f 1981- |g Aleksandra Gennadievna |3 (RuTPU)RU\TPU\pers\32466 |9 16414 | |
| 701 | 1 | |a Nevskaya |b K. V. |g Ksenia Vladimirovna | |
| 701 | 1 | |a Efimova |b L. V. |g Lina Viktorovna | |
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| 701 | 1 | |a Shur |b V. Ya. |g Vladimir Yakovlevich | |
| 701 | 1 | |a Krasnov |b V. P. |g Viktor Pavlovich | |
| 701 | 1 | |a Ogorodova |b L. M. |g Lyudmila Mikhaylovna | |
| 712 | 0 | 2 | |a Национальный исследовательский Томский политехнический университет |b Институт физики высоких технологий |b Кафедра биотехнологии и органической химии |3 (RuTPU)RU\TPU\col\18693 |9 27146 |
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