Geochemical factors and incidence of sarcoidosis in Tomsk region
| Parent link: | European Respiratory Journal: offcial scientific Journal of the ERS Vol. 40.— 2012.— [1 р.] |
|---|---|
| Corporate Author: | |
| Other Authors: | , , , , |
| Summary: | Title screen Sarcoidosis incidence has been studied according over a 20-year period (528 patients without unhealthy working conditions). The incidence rate has been determined per 100000 of populations and compared to the geochemical data: 2126 measurements of 23 chemical elements (Na, Ca, Sc, Cr, Fe, Co, Zn, Br, Rb, Ag, Sb, Au, La, Th, U, Hf, Se, Hg, Ce, Sm, Eu, Yb, and Lu) were made by the neutron activation analysis in the dust-aerosol, soil and drinking water in Tomsk and Tomsk region. Sarcoidosis highest incidence was found on the territories exposed to anthropogenic factors: in Seversk 67.3 (nuclear fuel industries), Octyabrsky district of Tomsk 56.8, Tomsk rural district 68.14, Strezhevoy 47.2 (fuel and oil industries). In these districts the incidence rate was significantly higher compared to the mean findings in region - 42.6 (χ ² = 7.94-11.6; p <0.05). The incidence in the mainly agricultural districts was minimal 23.5. In Seversk recurrent forms were significantly higher - 20.56 versus 10.23 in Tomsk (χ ² = 7,94; p <0,01). The correlations have been found between: the sarcoidosis incidence and the Na content in the dust aerosols (r = 0.9; p <0.05), Ce in the soils of industrial territories (r = 0.9; p <0.05), Ca in drinking water (r = 0.8; p <0.01); recurrent forms of sarcoidosis and Lu in soils of the contaminated territories (r = 0.8; p <0.05), Cr in soils of agrarian districts (r = 0.65; p <0.05). Thus, the correlation between the ecological state of the territories and sarcoidosis incidence is sure to exist. Uncertainty of the obtained data does not allow understanding which factor plays the role. One cannot deny the influence of trace elements which have shown the correlations: Na, Ca, Lu, Ce, Cr. |
| Published: |
2012
|
| Subjects: | |
| Online Access: | http://erj.ersjournals.com/content/40/Suppl_56/P4028.short |
| Format: | Electronic Book Chapter |
| KOHA link: | https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=642761 |