Development of Magnetic-Resonance Contrast Composition Based on Disodium Salt of Gd-DTPA
| Parent link: | Advanced Materials Research : Radiation and nuclear techniques in material science: Scientific Journal Vol. 1084 : Physical-Technical Problems of Nuclear Science, Energy Generation, and Power Industry (PTPAI -2014).— 2015.— [P. 549-553] |
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| Outros Autores: | , |
| Resumo: | Title screen In this research we have studied contrast composition in the form of an aqueous solution containing gadolinium oxide (Gd[2]O[3]), diethylenetriaminepentaacetic acid (DTPA), medical polymer - polyvinylpyrrolidone mol. sq. (12000 ± 5000) daltons in an amount of 0.5-5 wt. %. To reduce the content of free gadolinium in the composition it has been suggested to change the stoichiometric ratio of the concentrations of DTPA/Gd[2]O[3] in the mixture. The studies have shown that at a concentration ratio of DTPA/Gd[2]O[3], 2.07 - 2.10 the impurity content of free gadolinium is at least 0.25%, which is significantly below the regulated value - 0.5%. The conducted biomedical tests have confirmed the functionality of the resulting contrast composition. Режим доступа: по договору с организацией-держателем ресурса |
| Idioma: | inglês |
| Publicado em: |
2015
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| Colecção: | Radiation Technologies in Medicine |
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| Acesso em linha: | http://dx.doi.org/10.4028/www.scientific.net/AMR.1084.549 |
| Formato: | Recurso Electrónico Capítulo de Livro |
| KOHA link: | https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=640458 |
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| 200 | 1 | |a Development of Magnetic-Resonance Contrast Composition Based on Disodium Salt of Gd-DTPA |f V. S. Skuridin, E. S. Stasyuk (Stasiuk), V. I. Chernov | |
| 203 | |a Text |c electronic | ||
| 225 | 1 | |a Radiation Technologies in Medicine | |
| 300 | |a Title screen | ||
| 330 | |a In this research we have studied contrast composition in the form of an aqueous solution containing gadolinium oxide (Gd[2]O[3]), diethylenetriaminepentaacetic acid (DTPA), medical polymer - polyvinylpyrrolidone mol. sq. (12000 ± 5000) daltons in an amount of 0.5-5 wt. %. To reduce the content of free gadolinium in the composition it has been suggested to change the stoichiometric ratio of the concentrations of DTPA/Gd[2]O[3] in the mixture. The studies have shown that at a concentration ratio of DTPA/Gd[2]O[3], 2.07 - 2.10 the impurity content of free gadolinium is at least 0.25%, which is significantly below the regulated value - 0.5%. The conducted biomedical tests have confirmed the functionality of the resulting contrast composition. | ||
| 333 | |a Режим доступа: по договору с организацией-держателем ресурса | ||
| 461 | 1 | |0 (RuTPU)RU\TPU\network\4598 |t Advanced Materials Research : Radiation and nuclear techniques in material science |o Scientific Journal | |
| 463 | 1 | |0 (RuTPU)RU\TPU\network\4600 |t Vol. 1084 : Physical-Technical Problems of Nuclear Science, Energy Generation, and Power Industry (PTPAI -2014) |o The VIth International Conference, June 5-7, 2014, Tomsk, Russia |o [proceedings] |f National Research Tomsk Polytechnic University (TPU) |v [P. 549-553] |d 2015 | |
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| 700 | 1 | |a Skuridin |b V. S. |c Physicist, Specialist in the field of nuclear power engineering |c Professor of Tomsk Polytechnic University, Doctor of technical sciences |f 1946- |g Viktor Sergeyevich |3 (RuTPU)RU\TPU\pers\32655 |9 16554 | |
| 701 | 1 | |a Stasyuk (Stasiuk) |b E. S. |c Specialist in the field of nuclear power engineering |c Researcher of Tomsk Polytechnic University, Candidate of technical sciences |f 1978- |g Elena Sergeyevna |3 (RuTPU)RU\TPU\pers\32656 |9 16555 | |
| 701 | 1 | |a Chernov |b V. I. |c specialist in the field of medical technology |c lead engineer of Tomsk Polytechnic University, doctor of medical sciences |f 1962- |g Vladimir Ivanovich |3 (RuTPU)RU\TPU\pers\34191 | |
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