Development of Magnetic-Resonance Contrast Composition Based on Disodium Salt of Gd-DTPA
| Parent link: | Advanced Materials Research : Radiation and nuclear techniques in material science: Scientific Journal Vol. 1084 : Physical-Technical Problems of Nuclear Science, Energy Generation, and Power Industry (PTPAI -2014).— 2015.— [P. 549-553] |
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| Summary: | Title screen In this research we have studied contrast composition in the form of an aqueous solution containing gadolinium oxide (Gd[2]O[3]), diethylenetriaminepentaacetic acid (DTPA), medical polymer - polyvinylpyrrolidone mol. sq. (12000 ± 5000) daltons in an amount of 0.5-5 wt. %. To reduce the content of free gadolinium in the composition it has been suggested to change the stoichiometric ratio of the concentrations of DTPA/Gd[2]O[3] in the mixture. The studies have shown that at a concentration ratio of DTPA/Gd[2]O[3], 2.07 - 2.10 the impurity content of free gadolinium is at least 0.25%, which is significantly below the regulated value - 0.5%. The conducted biomedical tests have confirmed the functionality of the resulting contrast composition. Режим доступа: по договору с организацией-держателем ресурса |
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2015
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| Series: | Radiation Technologies in Medicine |
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| Online Access: | http://dx.doi.org/10.4028/www.scientific.net/AMR.1084.549 |
| Format: | Electronic Book Chapter |
| KOHA link: | https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=640458 |