Use of Autoleukocyte, Labelled with {99m}Tc-Exametazine for Evaluation of Inflammatory Changes in Myocardium

Bibliographic Details
Parent link:Advanced Materials Research : Radiation and nuclear techniques in material science: Scientific Journal
Vol. 1084 : Physical-Technical Problems of Nuclear Science, Energy Generation, and Power Industry (PTPAI -2014).— 2015.— [P. 511-514]
Corporate Author: Национальный исследовательский Томский политехнический университет (ТПУ) Физико-технический институт (ФТИ) Лаборатория № 31 ядерного реактора (Лаборатория № 31 ЯК)
Other Authors: Sazonova S. I. Svetlana Ivanovna, Lishmanov Yu. B. Yury Borisovich, Iljyushenkova Yu. N. Yuliya Nikolaevna, Batalov R. E., Rogovskaya Y. V.
Summary:Title screen
Our purpose was to study possibilities of autoleukocyte, labelled in vitro with {99m} Tc-exametazine ({99m} Tc-HMPAO), in evaluation of inflammatory changes of myocardium at patients with persistent form of atrial fibrillation (AF).We examined 30 patients with idiopathic persistent form of AF. For identification of the inflammatory areas in a myocardium before ablation scintigraphy (SPECT) {99m}Tc-HMPAO – leucocytes was carried out. Upon completion of scanning a perfusion scintigraphy of a myocardium with a {99m}Tc-methoxyisobutyl isonitrile ({99m}Tc-MIBI) (‘Tehnetril, {99m}Tc’, JSC Diamed, Russia) in rest under the standard protocol was carried out. Pathologic accumulation of {99m}Tc-HMPAO-leukocytes in a myocardium was revealed at 6 (20%) of the examined patients. Sensitivity of SPECT with {99m}Tc-HMPAO-leukocytes in diagnostics of inflammatory changes of a myocardium, according to our data, was - 80%, specificity - 92%, diagnostic accuracy - 90%.
Режим доступа: по договору с организацией-держателем ресурса
Published: 2015
Series:Radiation Technologies in Medicine
Subjects:
Online Access:http://dx.doi.org/10.4028/www.scientific.net/AMR.1084.511
Format: Electronic Book Chapter
KOHA link:https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=640429