Single-Photon Emission Computed Tomography and {99m}Tc-Methoxy-Isobutyl-Isonitrile in the Detection and Forecast of Cardiotoxicity of Chemotherapeutic Agents

Bibliographic Details
Parent link:Advanced Materials Research : Radiation and nuclear techniques in material science: Scientific Journal
Vol. 1084 : Physical-Technical Problems of Nuclear Science, Energy Generation, and Power Industry (PTPAI -2014).— 2015.— [P. 471-475]
Corporate Author: Национальный исследовательский Томский политехнический университет (ТПУ) Физико-технический институт (ФТИ) Лаборатория № 31 ядерного реактора (Лаборатория № 31 ЯК)
Other Authors: Chernov V. I. Vladimir Ivanovich, Kravchuk T. V., Zelchan R. V. Roman Vladimirovich, Podoplekin D. M., Goldberg V. E.
Summary:Title screen
To compare the possibility of using multiple-gated acquisition (MUGA) scan and Tc-99m MIBI gated SPECT for evaluation and forecast of anthracycline–induced cardiotoxicity. For the treatment of these patients we used doxorubicin in combination with various drugs. All patients were examined by MUGA or Gated SPECT before starting chemotherapy, at 1 hour after the first administration of doxorubicin and after the 4th course. The MUGA and Gated SPECT can be applied with equal efficiency for evaluation of acute and chronic anthracycline–induced cardiotoxicity in patients with malignant tumors. The decrease in LVEF (10% or more) in response to the first dose of doxorubicin can predict the development of chronic cardiotoxicity.
Режим доступа: по договору с организацией-держателем ресурса
Language:English
Published: 2015
Series:Radiation Technologies in Medicine
Subjects:
Online Access:http://dx.doi.org/10.4028/www.scientific.net/AMR.1084.471
Format: Electronic Book Chapter
KOHA link:https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=640415