Voltammetric Sensor for Total Cholesterol Determination

Bibliografski detalji
Parent link:Procedia Chemistry
Vol. 10 : Chemistry and Chemical Engineering in XXI century.— 2014.— [P. 513-518]
Autor kompanije: Национальный исследовательский Томский политехнический университет (ТПУ) Институт природных ресурсов (ИПР) Кафедра физической и аналитической химии (ФАХ)
Daljnji autori: Derina K. V. Kseniya Vladimirovna, Korotkova E. I. Elena Ivanovna, Dorozhko E. V. Elena Vladimirovna, Voronova O. A. Olesya Aleksandrovna, Vishenkova D. A. Dariya Aleksandrovna
Sažetak:Title screen
We report on a voltammetric sensor for the detection of total cholesterol. The sensor was fabricated by co-immobilization of two enzymes: cholesterol oxidase (ChOx) and horseradish peroxidase (HRP) on porous graphite. The electrochemical behavior of the sensor was studied with the use of linear sweep voltammetry. It has been shown that the sensor has high stability and high sensitivity (16 muA mM{-1} cm{-2}). The biosensor exhibited a wide linear range up to 300 mol/dm3 in a condition close to physiological (pH=6.86). Besides, the interferences of some key analytes containing in the blood were studied. As a matter of fact, making a fabricated sensor is rather promising for using in clinical practice.
Режим доступа: по договору с организацией-держателем ресурса
Izdano: 2014
Teme:
Online pristup:http://dx.doi.org/10.1016/j.proche.2014.10.087
http://earchive.tpu.ru/handle/11683/35541
Format: Elektronički Poglavlje knjige
KOHA link:https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=639559