Peculiarities of Adrenergic Regulation of Smooth Muscles in Rabbit Pulmonary Arteries

Peculiarities of Adrenergic Regulation of Smooth Muscles in Rabbit Pulmonary Arteries

التفاصيل البيبلوغرافية
Parent link:Bulletin of Experimental Biology and Medicine: Scientific Journal
Vol. 133, iss. 3.— 2002.— [P. 214-216]
مؤلفون آخرون: Kapilevich L. V. Leonid Vladimirovich, Nosarev A. V. Aleksey Valerievich, Diyakova (D'yakova) E. Yu. Elena Yurievna, Kovalev I. V., Baskakov M. B. Mikhail Borisovich, Anfinogenova Ya. J. Yana Jonovna, Medvedev M. A.
الملخص:Title screen
Muscle tension recording was used to study adrenergic contractile reactions of pulmonary artery smooth muscles in rabbits. Stimulation of alpha-adrenoceptors induced contraction of pulmonary artery smooth muscle cells. Endothelium partially inhibited the contractile effect of alpha-adrenoceptor agonists. Activation of smooth muscle beta-adrenoceptors in pulmonary arteries produced a dual dose-dependent effect (relaxation at agonist concentrations of 10 nM-1 muM and contraction at concentrations above 10 muM). The contractile effect of beta-adrenoceptor activation in smooth muscle cells is a specific feature of pulmonary arteries probably related to peculiarities of cAMP-signaling in these cells.
Режим доступа: по договору с организацией-держателем ресурса
منشور في: 2002
الموضوعات:
электронный ресурс
труды учёных ТПУ
pulmonary arteries
smooth muscles
adrenoceptors
endothelium
cAMP
الوصول للمادة أونلاين:http://link.springer.com/article/10.1023/A:1015862028565
التنسيق: الكتروني فصل الكتاب
KOHA link:https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=639218

الانترنت

http://link.springer.com/article/10.1023/A:1015862028565

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