Effect of Inhibitors of Cyclic Nucleotide Phosphodiesterases on Electrical and Contractile Activity of Smooth Muscle Cells; Bulletin of Experimental Biology and Medicine; Vol. 133, iss. 1

Effect of Inhibitors of Cyclic Nucleotide Phosphodiesterases on Electrical and Contractile Activity of Smooth Muscle Cells; Bulletin of Experimental Biology and Medicine; Vol. 133, iss. 1

Dettagli Bibliografici
Parent link:Bulletin of Experimental Biology and Medicine: Scientific Journal
Vol. 133, iss. 1.— 2002.— [P. 38-40]
Altri autori: Kovalev I. V., Popov A. G., Baskakov M. B. Mikhail Borisovich, Minochenko I. L., Kilin A. A., Borodin Yu. L., Anfinogenova Ya. J. Yana Jonovna, Kapilevich L. V. Leonid Vladimirovich, Medvedev M. A.
Riassunto:Title screen
Double sucrose gap experiments were carried out to study the effect of phosphodiesterase inhibitors and penetrating analogs of cyclic nucleotides on action potential and contraction of guinea pig ureteral smooth muscle cells. 3-Isobutyl-1-methylxanthine (10 µM) and dibutyryl-cAMP (20 µM) shortened the plateau of action potential and inhibited contraction of smooth muscle cells by increasing potassium permeability of their membrane. Vinpocetine (1 µM) and dibutyryl-cAMP (100 µM) strengthened contraction of smooth muscle cells and shortened action potentials by decreasing sodium permeability of their membrane.
Режим доступа: по договору с организацией-держателем ресурса
Lingua:inglese
Pubblicazione: 2002
Soggetti:
электронный ресурс
труды учёных ТПУ
smooth muscle cells
cyclic nucleotide phosphodiesterases
membrane ionic permeability
Accesso online:http://link.springer.com/article/10.1023/A:1015196125469
Natura: Elettronico Capitolo di libro
KOHA link:https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=639206

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