Effect of Inhibitors of Cyclic Nucleotide Phosphodiesterases on Electrical and Contractile Activity of Smooth Muscle Cells

Bibliographic Details
Parent link:	Bulletin of Experimental Biology and Medicine: Scientific Journal Vol. 133, iss. 1.— 2002.— [P. 38-40]
Other Authors:	Kovalev I. V., Popov A. G., Baskakov M. B. Mikhail Borisovich, Minochenko I. L., Kilin A. A., Borodin Yu. L., Anfinogenova Ya. J. Yana Jonovna, Kapilevich L. V. Leonid Vladimirovich, Medvedev M. A.
Summary:	Title screen Double sucrose gap experiments were carried out to study the effect of phosphodiesterase inhibitors and penetrating analogs of cyclic nucleotides on action potential and contraction of guinea pig ureteral smooth muscle cells. 3-Isobutyl-1-methylxanthine (10 µM) and dibutyryl-cAMP (20 µM) shortened the plateau of action potential and inhibited contraction of smooth muscle cells by increasing potassium permeability of their membrane. Vinpocetine (1 µM) and dibutyryl-cAMP (100 µM) strengthened contraction of smooth muscle cells and shortened action potentials by decreasing sodium permeability of their membrane. Режим доступа: по договору с организацией-держателем ресурса
Language:	English
Published:	2002
Subjects:	электронный ресурс труды учёных ТПУ smooth muscle cells cyclic nucleotide phosphodiesterases membrane ionic permeability
Online Access:	http://link.springer.com/article/10.1023/A:1015196125469
Format:	Electronic Book Chapter
KOHA link:	https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=639206

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