Effect of Na+,K+,2Cl- Cotransport Inhibitor Bumetanide on Electrical and Contractile Activity of Smooth Muscle Cells in Guinea Pig Ureter

Dades bibliogràfiques
Parent link:	Bulletin of Experimental Biology and Medicine: Scientific Journal Vol. 136, iss. 2.— 2003.— [P. 145-149]
Altres autors:	Kovalev I. V., Baskakov M. B. Mikhail Borisovich, Borodin Yu. L., Kilin A. A., Minochenko I. L., Popov A. G., Anfinogenova Ya. J. Yana Jonovna, Medvedev M. A., Orlov S. N., Kapilevich L. V. Leonid Vladimirovich
Sumari:	Title screen The effect of Na+,K+,2Cl- cotransport inhibitor bumetanide on action potentials and contractions of smooth muscle cells in the ureter of guinea pigs evoked by electrical stimulation was studied by the method of double sucrose bridge. Bumetanide (10-100 µM) dose-dependently suppressed action potential and contractions of smooth muscle cells induced by 1-10 µM histamine, 10 µM mesatone, 5 mM tetraethylammonium, and 100 µM sodium nitroprusside. Our findings suggest that test substances modulate Na+,K+,2Cl- cotransport in smooth muscle cells. Режим доступа: по договору с организацией-держателем ресурса
Idioma:	anglès
Publicat:	2003
Matèries:	электронный ресурс труды учёных ТПУ bumetanide biologically active substances smooth muscle cells
Accés en línia:	http://link.springer.com/article/10.1023/A:1026310722105
Format:	Electrònic Capítol de llibre
KOHA link:	https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=639199

Descripció
Sumari:	Title screen The effect of Na+,K+,2Cl- cotransport inhibitor bumetanide on action potentials and contractions of smooth muscle cells in the ureter of guinea pigs evoked by electrical stimulation was studied by the method of double sucrose bridge. Bumetanide (10-100 µM) dose-dependently suppressed action potential and contractions of smooth muscle cells induced by 1-10 µM histamine, 10 µM mesatone, 5 mM tetraethylammonium, and 100 µM sodium nitroprusside. Our findings suggest that test substances modulate Na+,K+,2Cl- cotransport in smooth muscle cells. Режим доступа: по договору с организацией-держателем ресурса

Ítems similars