Effect of Na+,K+,2Cl- Cotransport Inhibitor Bumetanide on Electrical and Contractile Activity of Smooth Muscle Cells in Guinea Pig Ureter
| Parent link: | Bulletin of Experimental Biology and Medicine: Scientific Journal Vol. 136, iss. 2.— 2003.— [P. 145-149] |
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| Other Authors: | , , , , , , , , , |
| Summary: | Title screen The effect of Na+,K+,2Cl- cotransport inhibitor bumetanide on action potentials and contractions of smooth muscle cells in the ureter of guinea pigs evoked by electrical stimulation was studied by the method of double sucrose bridge. Bumetanide (10-100 µM) dose-dependently suppressed action potential and contractions of smooth muscle cells induced by 1-10 µM histamine, 10 µM mesatone, 5 mM tetraethylammonium, and 100 µM sodium nitroprusside. Our findings suggest that test substances modulate Na+,K+,2Cl- cotransport in smooth muscle cells. Режим доступа: по договору с организацией-держателем ресурса |
| Published: |
2003
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| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1023/A:1026310722105 |
| Format: | Electronic Book Chapter |
| KOHA link: | https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=639199 |